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Protein Alignment Ir21a and Grik1

DIOPT Version :9

Sequence 1:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	644	Identity:	141/644 - (21%)
Similarity:	243/644 - (37%)	Gaps:	145/644 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 LGPQTESRVVLVSRSTQW---------RLRDFLSSELSSNIVNLLVIGESLMADPMRERPYVLYT 237
            |||    |.:.:.:..:|         ...|.|..:...:|::|...|....:..:.:..|.::
  Rat   356 LGP----RFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVW- 415

  Fly   238 HKLYADGL-GSNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDS 301
            .|:   |: .||:.:.:|.   |...|.: |:..|     .|.....::...:.|::. .|..|.
  Rat   416 KKI---GIWNSNSGLNMTD---GNRDRSN-NITDS-----LANRTLIVTTILEEPYVM-YRKSDK 467

  Fly   302 SGMGQLRWDGVEFRLLTMISKRLNFSIDITETPT----RSNTRGVVDTIQEQIIERTVDIGMSGI 362
            ...|..|::|....||..:|..|.|..|:...|.    ..|.:|..:.:.:::|:...|:.::.:
  Rat   468 PLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPL 532

  Fly   363 YIT--QERLMDSAMSVGHSPDCAAFITLASKAL--------PKYRAIMGPFQWPVWVALICVYLG 417
            .||  :|:::|.:         ..|:||....|        |...:.:.|....:|:.::...||
  Rat   533 TITYVREKVIDFS---------KPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLG 588

  Fly   418 GIFPIVFTDRLTL------------SHLMGNWGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNS 470
            ....:....|.|.            |.::.|...:.|.||:..|      :...:.|....:..|
  Rat   589 VSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVG------ALMQQGSELMPKALS 647

  Fly   471 TRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNNGGWETWFQNS 534
            ||::.|.:|.||:||.|.||.::.||:|:......:||..||. ......|.:.:|...|:|:.|
  Rat   648 TRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKS 712

  Fly   535 THIPTSRLYKKM----------EFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENI 589
             .|.|   |:||          ..|.:.||||..|..:   :||.|.....:||:.|.|.:
  Rat   713 -KIST---YEKMWAFMSSRQQSALVKNSDEGIQRVLTT---DYALLMESTSIEYVTQRNCN---- 766

  Fly   590 SRRSALHLSEECFALFQIGFLF---------PRESVYKIKIDSMILLAQQSGLIAKINNEVSWVM 645
                          |.|||.|.         |..|.|:.||...||..|:.|.: .:..|..|
  Rat   767 --------------LTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKL-HMMKEKWW-- 814

  Fly   646 QRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQI 710
                       ..:....|..:|...|...:..|:|:::|.|..|.....:.|           .
  Rat   815 -----------RGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGE-----------F 857

  Fly   711 IKRSRKSAASSWSSASSGSMLRTNAEQLSHDKRKANRREAAEVAQKMSFG--MRELNLT 767
            :.:|||:........||........:...|..:|    |:..|.:.:||.  |.||.::
  Rat   858 LYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKK----ESLGVEKCLSFNAIMEELGIS 912

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.