Protein Alignment Ir21a and GRIN2C

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 117/633 - (18%)
• Similarity: 210/633 - (33%)
• Gaps: 187/633 - (29%)

  Fly   141 FYHGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRL---- 201
            ||...:|..:|.::..|:..         .:|..|.|.           |:.::|...|.:
Human   406 FYRHLLNVTWEGRDFSFSPG---------GYLVQPTMV-----------VIALNRHRLWEMVGRW 450

  Fly   202 -RDFLSSELS-----SNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGA 260
             ...|..:..     |..:..:|....|....:.|||:|:....  ..|.|...|
Human   451 EHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESP--DPGTGGCVP---------- 503

  Fly   261 LSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMISKRLN 325
                  |..|.:.|   :.|.|  |:.:..|:.            :|...|....:|..:::.:.
Human   504 ------NTVPCRRQ---SNHTF--SSGDVAPYT------------KLCCKGFCIDILKKLARVVK 545

  Fly   326 FSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQERLMDSAMSVGHSPDCAAFIT 387
            ||.|   :|........|||.:.:..::..:..|:.:..:.|.:||......||.......:.:.
Human   546 FSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMV 610

  Fly   388 LASKALPKYRAIMGPFQWPVWVAL---------ICVYLGGIF-PIVFTDRLTLSHLMGN------ 436
            ..|.......|.:.|:...|||.:         |.|::...| |:.:...||.....|.
Human   611 ARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKSGGPAFTIG 675

  Fly   437 ---WGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVT 498
               |     :.|        |..|.......|.|..::::::..:..|.:|..:.||.::.||:.
Human   676 KSVW-----LLW--------ALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMI 727

  Fly   499 LPAFPDTVDSVLDLLGLF----------------------------FRVGTLNNGGWETWFQNS- 534
            ...:.|||..:.|...|.                            ||.||:.||..|...:::
Human   728 QEQYIDTVSGLSDKKSLHLENTGVAWTAFKTFCSDYFQRPQDQYPPFRFGTVPNGSTERNIRSNY 792

  Fly   535 ----THIPTSRLYKKMEF-VGSVDEGIGNVTQSFFWNYAFLGSKAQ---------------LEYL 579
                ||:        ::| ..||::.:.::.         :||:||               |.|:
Human   793 RDMHTHM--------VKFNQRSVEDALTSLK---------MGSEAQPVPRKLDAFIYDAAVLNYM 840

  Fly   580 VQSNFSDENISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWV 644
            ...:...:.::..|.     :.||....|....::|.:|..||..:|.....|...|:  |..|
Human   841 AGKDEGCKLVTIGSG-----KVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKL--ETVW- 897

  Fly   645 MQRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMF--LLMALGYFL 690
                     |.....|...|::..  :|...:..|:|  ||:|:|..|
Human   898 ---------LSGICQNEKNEVMSS--KLDIDNMAGVFYMLLVAMGLAL 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	65/364 (18%)
		Lig_chan	407..662	CDD:278489	60/322 (19%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810