Protein Alignment Ir21a and Grin2d

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 119/610 - (19%)
• Similarity: 220/610 - (36%)
• Gaps: 149/610 - (24%)

  Fly   179 RKILGPQTESRVVLVSRSTQWRLRDF-LSSELSSN--IVNLLVIGESLMADPMRERPYVLYTHKL 240
            |..|..:..:.|.:|:|..|..|||: ...||..:  ..|....||||....|.    :.:.::.
  Rat   310 RDDLARRVAAGVAVVARGAQALLRDYGFLPELGHDCRTQNRTHRGESLHRYFMN----ITWDNRD 370

  Fly   241 YA---DGLGSNTPVVLTS------W-IKGALSRPHINL-FPSKFQFGFAGHRF----------QI 284
            |:   ||...|..:|:.|      | :.|:..:..:.| :|...::|    ||          .:
  Rat   371 YSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYG----RFLQPVDDTQHLTV 431

  Fly   285 SAANQPPFIFRIRTLDSSGMGQLRWDGVEFR---------------------------LLTMISK 322
            :...:.||:. :...|......:| |.|..|                           :|..::.
  Rat   432 ATLEERPFVI-VEPADPISGTCIR-DSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAH 494

  Fly   323 RLNFSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQER---------LMDSAMS 375
            .:.||.|   :|.........||.:.:..::..:..|:.:..:.|.:||         .:::.:|
  Rat   495 TIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGIS 559

  Fly   376 V-------GHSPDC-AAFITLASKALPKYRAIMGPFQWPVWVAL--ICVYLGGIFPIVF------ 424
            |       ..||.. .||..|.....|:      |:...|||.:  :|:.:..:...:|
  Rat   560 VMVARSNGTVSPSAFLAFAWLTPPMSPE------PYSPAVWVMMFVMCLTVVAVTVFIFEYLSPV 618

  Fly   425 ---TDRLTLSHLMGNWGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIIT 486
               ....|.....|:...:....|.::     |..|.......|.|..::::::..:..|.:|..
  Rat   619 GYNRSLATGKRPGGSTFTIGKSIWLLW-----ALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFL 678

  Fly   487 SCYTGSIIAFVTLPAFPDTVDSVLDLLGLF---------FRVGTLNNGGWETWFQNSTHIPTSRL 542
            :.||.::.||:....:.|||..:.|  ..|         .:.||:.||..|...:  ::.|....
  Rat   679 ASYTANLAAFMIQEEYVDTVSGLSD--RKFQRPQEQYPPLKFGTVPNGSTEKNIR--SNYPDMHS 739

  Fly   543 YKKMEFVGSVDEGI-----GNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECF 602
            |........|:|.:     |.:.       ||:...|.|.|:.:.:...:.::..|.     :.|
  Rat   740 YMVRYNQPRVEEALTQLKAGKLD-------AFIYDAAVLNYMARKDEGCKLVTIGSG-----KVF 792

  Fly   603 ALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQ 667
            |....|....:.|.:|..||  :.|.|..|     ::|:..:.:...||     ...|...|::.
  Rat   793 ATTGYGIALHKGSRWKRPID--LALLQFLG-----DDEIEMLERLWLSG-----ICHNDKIEVMS 845

  Fly   668 EERQLTTADTEGMF--LLMALGYFL 690
            .  :|...:..|:|  ||:|:|..|
  Rat   846 S--KLDIDNMAGVFYMLLVAMGLSL 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	65/365 (18%)
		Lig_chan	407..662	CDD:278489	53/279 (19%)
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	26/103 (25%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	79/451 (18%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900