Protein Alignment Ir21a and gria3a

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_005165152.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 903
• Species: Danio rerio
• Alignment Length: 576
• Identity: 109/576 - (18%)
• Similarity: 211/576 - (36%)
• Gaps: 168/576 - (29%)

  Fly   125 SDGLILENLFKTIPITFYHGEINADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKI-LGPQTES 188
            |.|:.:|...|.:.:....|.|..|...:...:|  :|       ::...|...||| ...:.|.
Zfish   342 SQGIDIERALKMVQVQGMTGNIQFDSFGRRSNYT--VD-------VYEMKPGGARKIGYWNEFEK 397

  Fly   189 RVVLVSRSTQWRLRDFLSSELSSNIVNLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVL 253
            .|.:|.:.        :::| ||::.|..::..::|     |.|||:|
Zfish   398 FVYIVEQQ--------VTNE-SSSVENRTIVVTTIM-----EAPYVMY----------------- 431

  Fly   254 TSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLT 318
                    .|.::.|                                   .|..|::|....|.:
Zfish   432 --------KRNYMQL-----------------------------------EGNDRYEGYCVDLAS 453

  Fly   319 MISKRLNFSIDIT---------ETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYIT--QERLMDS 372
            .|:|.:.....::         ..|......|:|.    :::....||.::.:.||  :|.::|.
Zfish   454 EIAKHVGIKYKLSIVADGKYGARDPETKTWNGMVG----ELVYGRADIAVAPLTITLVREEVIDF 514

  Fly   373 A---MSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGIFPIVFTDRLTLSHLM 434
            :   ||:|.|    ..|....|:.|...:.:.|..:.:|:.::..|: |:..::|        |:
Zfish   515 SKPFMSLGIS----IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI-GVSVVLF--------LV 566

  Fly   435 GNWGEVENMFWYV------------------FGMFTNAFSFTGKYSWS----NTRKNSTRLLIGA 477
            ..:...|   |::                  ||:|.:.:...|.:...    :.|..|.|::.|.
Zfish   567 SRFSPYE---WHLDDNEETKDPQTPPDPPNDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGV 628

  Fly   478 YWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNNGGWETWFQNSTHIPTSR 541
            :|.||:||.|.||.::.||:|:......::|..||. ......|||::|..:.:|:.|......:
Zfish   629 WWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEK 693

  Fly   542 LYKKME------FVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDE-----NISRRSAL 595
            ::..|:      ||.:..:|:..|.:| ...:|||......||:.|....|.     |:..:.
Zfish   694 MWSYMKSAEPSVFVKTTPDGVARVRKS-KGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKG-- 755

  Fly   596 HLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSG 651
                       .|...|:.|..:..::..:|...:.|::.|:.|:  |...:...|
Zfish   756 -----------YGVATPKGSALRTPVNLAVLKLSEQGILDKLKNK--WWYDKGECG 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	70/336 (21%)
		Lig_chan	407..662	CDD:278489	58/279 (21%)
gria3a	XP_005165152.1	PBP1_iGluR_AMPA_GluR3	28..399	CDD:107382	14/65 (22%)
		ANF_receptor	39..382	CDD:279440	9/48 (19%)
		PBP2_iGluR_AMPA	415..797	CDD:270433	89/482 (18%)
		Lig_chan	547..810	CDD:278489	58/280 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910