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Protein Alignment Ir21a and gria2b

DIOPT Version :9

Sequence 1:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	XP_005157361.1	Gene:	gria2b / 170451	ZFINID:	ZDB-GENE-020125-4	Length:	897	Species:	Danio rerio

Alignment Length:	536	Identity:	113/536 - (21%)
Similarity:	213/536 - (39%)	Gaps:	91/536 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 LGSNTPVVLTSW---IKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQ 306
            |.||..|.:..|   .|..:::.  :|||:. ..|.......::...:.|::...:..|.. |..
Zfish   376 LKSNGAVKIGYWNEVDKMVVTKS--DLFPND-TMGLENKTVIVTTILEAPYVMLKKNADLF-MDN 436

  Fly   307 LRWDGVEFRLLTMISKRLNFSIDI------------TETPTRSNTRGVVDTIQEQIIERTVDIGM 359
            .|::|....|...|:|...|...:            .||...:...|       :::....||.:
Zfish   437 ERYEGYCVDLAAEIAKHCGFKYQLKIVGDGKYGARDAETKIWNGMVG-------ELVYGKADIAV 494

  Fly   360 SGIYIT--QERLMDSA---MSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGI 419
            :.:.||  :|.::|.:   ||:|.|    ..|....|:.|...:.:.|..:.:|:.::..|:|..
Zfish   495 APLTITLVREEVIDFSKPFMSLGIS----IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 555

  Fly   420 FPIVFTDRLTLSHLMGNW-------GEVE-NMFWYVFGMFTNAFSFTGKYSWS----NTRKNSTR 472
            ..:....|.:    ...|       |::: |.....||:|.:.:...|.:...    :.|..|.|
Zfish   556 VVLFLVSRFS----PYEWHTEEYEDGQIQTNESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGR 616

  Fly   473 LLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNNGGWETWFQNSTH 536
            ::.|.:|.||:||.|.||.::.||:|:......::|..||. ......|||::|..:.:|:.|..
Zfish   617 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI 681

  Fly   537 IPTSRLYKKME------FVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDE-----NIS 590
            ....:::..|:      ||.:..||:..|.:| ...||:|......||:.|....|.     |:.
Zfish   682 ALFDKMWTYMKGAEPSVFVKTTAEGVMRVRKS-KGKYAYLLESTMNEYIEQRKPCDTMKVGGNLD 745

  Fly   591 RRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQ 655
            .:.             .|...|:.|..:..::..:|...:.||:.|:.|:  |...:...|
Zfish   746 SKG-------------YGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNK--WWYDKGECG---- 791

  Fly   656 ASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSAAS 720
             |.....:|   :...|:.::..|:|.::..|  ||...||:.:  ....|.|...||.:.:.:.
Zfish   792 -SGGGDSKE---KTSALSLSNVAGVFYILVGG--LGLAMLVALV--EFCYKSRAEAKRMKVTFSD 848

  Fly   721 SWSSASSGSMLRTNAE 736
            :..|.:..|:..:..|
Zfish   849 AMRSKARLSVTGSTGE 864

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.