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Protein Alignment Ir21a and gria2a

DIOPT Version :9

Sequence 1:	NP_001097043.1	Gene:	Ir21a / 33157	FlyBaseID:	FBgn0031209	Length:	842	Species:	Drosophila melanogaster
Sequence 2:	XP_005170953.1	Gene:	gria2a / 170450	ZFINID:	ZDB-GENE-020125-3	Length:	893	Species:	Danio rerio

Alignment Length:	556	Identity:	115/556 - (20%)
Similarity:	220/556 - (39%)	Gaps:	110/556 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 LGSNTPVVLTSW---IKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQ 306
            |.::.||.:..|   .|.|:::.  :|||:. ..|.......::...:.|::...:..:.....:
Zfish   372 LKNSGPVKIGYWNEMDKMAVTKS--DLFPND-TMGMENKTVIVTTILEAPYVMLKKNAELFTDNE 433

  Fly   307 LRWDGVEFRLLTMISKRLNFSIDI------------TETPTRSNTRGVVDTIQEQIIERTVDIGM 359
             |::|....|...|:|...|...:            .||...:...|       :::....||.:
Zfish   434 -RYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGARDAETKIWNGMVG-------ELVYGKADIAV 490

  Fly   360 SGIYIT--QERLMDSA---MSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGI 419
            :.:.||  :|.::|.:   ||:|.|    ..|....|:.|...:.:.|..:.:|:.::..|: |:
Zfish   491 APLTITLVREEVIDFSKPFMSLGIS----IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI-GV 550

  Fly   420 FPIVFTDRLTLSHLMGNWGEVENMFWYV----------------FGMFTNAFSFTGKYSWS---- 464
            ..::|        |:..:...|   |:.                ||:|.:.:...|.:...
Zfish   551 SVVLF--------LVSRFSPYE---WHTEEFEDGQLGPSESTNEFGIFNSLWFSLGAFMQQGCDI 604

  Fly   465 NTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLL-GLFFRVGTLNNGGWE 528
            :.|..|.|::.|.:|.||:||.|.||.::.||:|:......::|..||. ......|||:.|..:
Zfish   605 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDAGSTK 669

  Fly   529 TWFQNSTHIPTSRLYKKME------FVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDE 587
            .:|:.|......::::.|:      ||.:..||:..|.:| ...||:|......||:.|....|.
Zfish   670 EFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLRVRKS-KGKYAYLLESTMNEYIEQRKPCDT 733

  Fly   588 -----NISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQR 647
                 |:..:.             .|...|:.|..:..::..:|...:.||:.|:.|:  |...:
Zfish   734 MKVGGNLDSKG-------------YGIATPKGSALRNAVNLAVLKLNEQGLLDKLKNK--WWYDK 783

  Fly   648 SSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIK 712
            ...|     |.....:|   :...|:.::..|:|.::..|  ||...||:.:  ....|.|...|
Zfish   784 GECG-----SGGGESKE---KTSALSLSNVAGVFYILVGG--LGLAMLVALV--EFCYKSRAEAK 836

  Fly   713 RSRKSAASSWSSASSGSMLRTNAEQ---LSHDKRKA 745
            |.:.:...:..|.:..|:..:..|.   |:.|..||
Zfish   837 RMKMTFTDAMRSKARLSITGSTGENGRVLTPDFSKA 872

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.