Protein Alignment Ir21a and grin2ba

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001429729.1
• Gene: grin2ba / 110438919
• ZFINID: ZDB-GENE-090821-2
• Length: 1606
• Species: Danio rerio
• Alignment Length: 715
• Identity: 137/715 - (19%)
• Similarity: 236/715 - (33%)
• Gaps: 163/715 - (22%)

  Fly   135 KTIPITFYHGEI-----NADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESR--VVL 192
            |..|:|..:.|:     |..:|.:|..|:..                      |.|...:  ::|
Zfish   375 KKSPMTGNNNEVLRYLMNVTFEGRNLSFSED----------------------GYQMHPKLVIIL 417

  Fly   193 VSRSTQW-RLRDFLSSELSSNIVNL----LVIGESLMAD------PMRERPYVLYTHKLYADGLG 246
            :.:..|| |:..:.:..||......    |..|.....|      .:.|.|:|:
Zfish   418 LDKERQWDRVGKWENGSLSMKYHVWPRFELYSGPEAREDDHLSIVTLEEAPFVI----------- 471

  Fly   247 SNTPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDG 311
                |.....:.|...|   |..|.         |.|:.|.||        |.||:...:....|
Zfish   472 ----VEDVDPLSGTCMR---NTVPC---------RKQLKALNQ--------TQDSAVYIKRCCKG 512

  Fly   312 VEFRLLTMISKRLNFSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSGIYITQERLMDSA 373
            ....:|..|:|.:.|:.|   :|.........|..:.:..:::.:...:.:..:.|.:||.....
Zfish   513 FCIDILKKIAKNVKFTYDLYLVTNGKHGKKINGTWNGMVGEVVLKNAHMAVGSLTINEERSEVID 577

  Fly   374 MSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVW----VALICVYLGGIFPIVFTDRLTLSHLM 434
            .||.......:.:...|.......|.:.||...||    |.|:.|....:|...:...:..:..:
Zfish   578 FSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWIMMFVMLLLVSAIAVFIFEYFSPVGYNRCL 642

  Fly   435 GNWGE-------VENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTIIITSCYTGS 492
            .:..|       :....|.::|:.     |.......|.|..::::::..:..|.:|..:.||.:
Zfish   643 ADGREAGGPSFTIGKAIWLLWGLV-----FNNSVPVQNPRGTTSKIMVSVWAFFAVIFLASYTAN 702

  Fly   493 IIAFVTLPAFPDTVDSVLDL-------LGLFFRVGTLNNGGWETWFQNSTHIPTSRLYK-----K 545
            :.||:....:.|.|..:.|.       ....||.||:.||..|...:|:.....|.:.|     .
Zfish   703 LAAFMIQEEYVDQVSGLSDKKFQNPNDFSPPFRFGTVPNGSTERNIRNNYRDMHSYMVKFHQRNV 767

  Fly   546 MEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHL----SEECFALFQ 606
            :|.:.|:..|..:         ||:...|.|.|:.         .|.....|    |.:.||...
Zfish   768 VEALESLKTGKLD---------AFIYDAAVLNYMA---------GRDEGCKLVTIGSGKVFASTG 814

  Fly   607 IGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQEERQ 671
            .|....::|.:|.::|..||.....|.:.::  |..|          |.....:...|::..  |
Zfish   815 YGIAIQKDSGWKRQVDLAILQLFGDGEMEEL--EALW----------LTGICHHEKNEVMSS--Q 865

  Fly   672 LTTADTEGMFLLMALGYFLGATALVSEIVGGITNKCRQIIKRSRKSAASSWSSASSGSMLRTNAE 736
            |...:..|:|      |.|||...:|.    ||.....:.....:.......|...|.....:.|
Zfish   866 LDVDNMAGVF------YMLGAAMALSL----ITFIAEHVFYWHMRFCFMGVCSGKPGFTFTISRE 920

  Fly   737 QLS-------HDKRKANRREAAEVAQKMSFGMRELNLTRATLREIYGSYGAPETDHGQLDIVHTE 794
            ..|       .||..|....:|.:....|..:|.|. |...:..:.|..|:|   |..||.:..|
Zfish   921 IYSCIHGVEIEDKSSALNSPSATMNNTHSNILRLLR-TAKNMASLSGVNGSP---HSALDFIRRE 981

  Fly   795  794
            Zfish   982  981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	19/107 (18%)
		Lig_chan	405..662	CDD:459656	54/283 (19%)
grin2ba	NP_001429729.1	None