Protein Alignment Ir21a and grin3b

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 965
• Identity: 188/965 - (19%)
• Similarity: 321/965 - (33%)
• Gaps: 310/965 - (32%)

  Fly     5 WVALVLFTAQAFSIEGDRSASYQE------KCISRRLIN---------------HYQLNKE---- 44
            |..:.:.|...:.     |||.|.      ..:||.::|               |::..|.
 Frog   171 WEEVDIITCHPWD-----SASIQRYLTSNTTLVSRTILNIHPVDESALVPFLQQHFESMKNPQFP 230

  Fly    45 --IFGVGMCDGNNEN-EFRQKRRIVPTFQGNPRPRGELLASKFH------VNSYNFEQTNSLVGL 100
              ::|   ||....: .||..|..            .|.|.:||      :|...........||
 Frog   231 MLLYG---CDARRSSLVFRVARDC------------GLEAHEFHWMIGHPLNGEEMTTEGMPPGL 280

  Fly   101 V--NKIAQEYLNKCPPVIYYDSFVEKSDGLILENLFKTIPITFYHGEINADYEAKNKRFTSHIDC 163
            :  .::::..:.|         |:..:.||:...:...:       .:..|...    ..|.::|
 Frog   281 LAYGEVSRPTMEK---------FIRDAVGLVTRAISAAV-------HVRPDLAL----IQSMVNC 325

  Fly   164 NCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFLSSELSSNIVNLLVIGESLMADPM 228
            |.|          .|:     |.||....:||        ||::...|.....:.:..:|:   .
 Frog   326 NDK----------QTK-----QNESSGSYLSR--------FLANTSFSGQTGQIYVSNNLI---H 364

  Fly   229 RERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHINLFPSKFQ------FGFAGHRFQISAA 287
            .|..|.:::  |..|.||..|.|.:..|.:|.:.... .|:.|:.|      .|||..:.::...
 Frog   365 TEHHYRIWS--LVRDSLGDPTWVTVGGWRQGKMEVEE-GLWQSRIQQWEPAPGGFARTKLRVVTL 426

  Fly   288 NQPPFIFRIRTLDSSG---MGQLRWD-----------------------GVEFR---------LL 317
            .:.||:| .|.:|:.|   .||:..|                       .:|::         ||
 Frog   427 VEHPFVF-TREVDADGSCPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLL 490

  Fly   318 TMISKRLNFSIDI-----TETPTRSNTR--GVV-----------------DTIQEQIIERTVDIG 358
            ..:|:.|.|..::     .:...|...|  |:|                 ::.:..:|:.|
 Frog   491 EKLSEDLRFDFELYIVGDGKYGARKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFT---- 551

  Fly   359 MSGIYITQ----ERLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVALICVYLGGI 419
             |..|.|.    .|:.|:|..:|                    |.|.|..|.:||        ||
 Frog   552 -SPFYSTSLGILVRMRDTASPIG--------------------AFMWPLHWSMWV--------GI 587

  Fly   420 FPIVFTDRLTLSHLMGNWGEVENMFWYVFGMF------TNAFSFT-----------GKYSWSNTR 467
            |..:....|.|:..  .|..       .|||.      |..||::           |:...|.|.
 Frog   588 FVALHITALFLTFY--EWKS-------PFGMTPHGRNRTKIFSYSSALNLCYAILFGRTVSSKTP 643

  Fly   468 KNST-RLLIGAYWLFTIIITSCYTGSIIAFV----TLPAFPDTVDSVLDLLGLFFRVGTLNNGGW 527
            |..| |:|:..:.:|.:::.|.||.::.|.:    |..|.....|..|......||.||:.....
 Frog   644 KCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEALSGIHDPKLHHPSQGFRFGTVWESSA 708

  Fly   528 ETWFQNSTHIPTSRLYKKMEFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRR 592
            |.:.:.|  .|....|.:...|.:..:|:..:........||:..||.|:|.|.
 Frog   709 EQYIKKS--FPEMHNYMRKFSVPATSDGVHLLKTDPPTLNAFIMDKALLDYEVS----------- 760

  Fly   593 SALHLSEEC--------FALFQIGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSS 649
                :..:|        ||:...|...|:.|.....|...|...:.||.:..::::  | .:...
 Frog   761 ----IDSDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLHDK--W-YKMVP 818

  Fly   650 SGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFLGA--TALVSEIVGGITNKCRQIIK 712
            .|:.:.|         :.|..|:......|:|:|:.:| |.|:  |:|:..:|..:      |:.
 Frog   819 CGKRVYA---------VTETLQMGIYHFSGLFVLLCIG-FCGSLLTSLMERVVYHL------ILP 867

  Fly   713 RSRKSAASSW---SSASSGSMLRTNAEQLSHDKRKANRR-----EAAEVAQKMSFGMR------- 762
            |.|:.....:   :|......|....|.......|.|:|     :|....|.:...:|
 Frog   868 RIRRRRRFKYWLHTSQKIHRALNMTCEDQDALSPKLNKRCNLQKDATGAPQSVWNNLRRTPAHQE 932

  Fly   763 ---ELNLTRATLREIYGSYGAPETDHGQLDIVHTEFPNSSAKLNNIEDEESREAL 814
               ..||.:|:.||.....|.|:      .|...|......|:..:: |:.|.||
 Frog   933 RRVHFNLEKASAREGLCENGRPK------GIKQEELKELEVKIEGMK-EQLRAAL 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	79/378 (21%)
		Lig_chan	407..662	CDD:278489	60/284 (21%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	53/299 (18%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	90/458 (20%)
		Lig_chan	582..848	CDD:395014	66/312 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910