Protein Alignment Ir21a and grid2

DIOPT Version :9

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 124/638 - (19%)
• Similarity: 223/638 - (34%)
• Gaps: 183/638 - (28%)

  Fly   240 LYADGLGSN---------------TPVVLTSWIKGALSRPHINLFPSKFQFGFAGHRFQISAANQ 289
            :|.:.||:|               .||   :.:.|:|:       ..|.:....|...:::...:
 Frog   396 IYFEILGTNYGEELGRGIRKLGFWNPV---TGLNGSLT-------DRKLENNMRGVVLRVATVLE 450

  Fly   290 PPFIFRIRTLDSSGMGQ-LRWDGVEFRLLTMISKRLNFSIDITETPTRSNTRGVVD-----TIQE 348
            .||:.    :..:.:|: .::.|....:|..:|..|.|..:|.............|     .|.|
 Frog   451 EPFVM----VSENVLGKPKKYQGFSIDVLDALSSYLGFKYEIYVASDHKYGSPQADGSWNGLIGE 511

  Fly   349 QIIERTVDIGMSGIYITQE---------RLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQ 404
            .:::| .|:|:|.:.||.:         |.||.::.|        .:..|.|.:..: |.:.||.
 Frog   512 LLLKR-ADMGISALTITPDRENVVDFTTRYMDYSVGV--------LLRKAEKTVDMF-ACLAPFD 566

  Fly   405 WPVW---------VALICVYLGGIFPIVFTDRLTLSHLMGNWGEVENMFWYVFGMFTNAFSFTGK 460
            ..:|         |.|:...|..:.|    .||.:..:...  .:.|..|:|:|.|...   .|:
 Frog   567 LSLWACIAGTVLLVGLLVYLLNWLNP----PRLQMGSMTST--TLYNSMWFVYGSFVQQ---GGE 622

  Fly   461 YSWSNTRKNSTRLLIGAYWLFTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLFFRVGTLNNG 525
            ..::..   :||:::||:|||.:|:.|.||.::.||:|:.....::.|:.||
 Frog   623 VPYTTL---ATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQDL------------- 671

  Fly   526 GWETWFQNSTHIP-----TSRLYKKMEFVG-------------------------SVDEGIGNVT 560
                  ...|.||     .|.:|:.:...|                         :|.|.:..:.
 Frog   672 ------SRQTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINRSNGSENNVQESLEGIQ 730

  Fly   561 QSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECFALFQIGFLFPRESVYKIKIDSMI 625
            :....||||:...|.|||:.   .:|::.|    .:......|....|......|.|:......|
 Frog   731 KVKHGNYAFVWDAAVLEYIA---INDQDCS----FYTVGNTIADRGYGIALQHGSPYRDIFSQRI 788

  Fly   626 LLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQEERQLTTADTEGMFLLMALGYFL 690
            |..||:|.:..:.::  | ..|:....|      :|..:..|:...|......|:|.::|.|..|
 Frog   789 LELQQNGDMDILKHK--W-WPRNGQCEL------HSSMDTKQKGSSLDIKSFSGVFCILAAGIVL 844

  Fly   691 GATALVSEIVGGITNKCRQIIKRSRKSAASSWSSASSGSMLRTNAE----QLSHDKRKANRREAA 751
            .....:.|                      :|.:...||.:.:..:    .|.|..|:.|.....
 Frog   845 SCFIAMVE----------------------TWWNKKKGSRVPSKEDDKEIDLEHLHRRVNSLCTD 887

  Fly   752 EVAQKMSFGMRELNLT---------RATLREIYGSYGAPETDHGQLDIVHTEF 795
            :.:....|....::||         |.||.:|        :|.....|..|.|
 Frog   888 DESPHKQFSTSSIDLTPLDIDSLPNRQTLEQI--------SDFRNTHITTTTF 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	73/347 (21%)
		Lig_chan	407..662	CDD:278489	60/293 (20%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	7/35 (20%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	86/420 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910