Protein Alignment Ir21a and grin2db

DIOPT Version :10

• Sequence 1: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_073782035.1
• Gene: grin2db / 100149482
• ZFINID: ZDB-GENE-100920-7
• Length: 1984
• Species: Danio rerio
• Alignment Length: 677
• Identity: 117/677 - (17%)
• Similarity: 223/677 - (32%)
• Gaps: 203/677 - (29%)

  Fly   143 HGEI--NADYEAKNKRFTSHIDCNCKSYILFLSDPLMTRKILGPQTESRVVLVSRSTQWRLRDFL 205
            ||.:  ..||.|..   ..|...||:      :|...|::|.|                |:|.|
Zfish   354 HGAVALRKDYGATG---GPHFVTNCQ------TDGNRTQRIRG----------------RMRYF- 392

  Fly   206 SSELSSNIV----NLLVIGESLMADPMRERPYVLYTHKLYADGLGSNTPVVLTSWIKGALSRPHI 266
                 |||.    :.....|..:|:|..:  .:.||.       ||....|  .|.:..:.|..
Zfish   393 -----SNITLGGRDYSFSNEGYLANPFLD--VISYTP-------GSGWEDV--GWWENGVLRLR- 440

  Fly   267 NLFPSKFQFG-------FAGHRFQISAANQPPFIFRIRTLDSSGMGQLRWDGVEFR--------- 315
              :|:..::|       .|.| .::....:.||:  |..|..:..|....|.|..|
Zfish   441 --YPAWSRYGPFLQPPDDAQH-LRVVTLEERPFV--IVELADAASGTCIRDSVPCRRPLNASALQ 500

  Fly   316 ----------------LLTMISKRLNFSID---ITETPTRSNTRGVVDTIQEQIIERTVDIGMSG 361
                            :|..:::.:.|:.|   :|.........||.:.:..:::.:..|:.:..
Zfish   501 EGVAPVKQCCKGFCIDILKRLARIVGFTYDLYLVTNGKHGKKIDGVWNGMVGEVVYKRADMAIGS 565

  Fly   362 IYITQERLMDSAMSVGHSPDCAAFITLASKALPKYRAIMGPFQWPVWVAL---------ICVYLG 417
            :.|.:||......||.......:.:...|.......|.:.|:...|||.:         :.|::.
Zfish   566 LTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIF 630

  Fly   418 GIFPIVFTDRLTLS--HLMGNWGEVENMFWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWL 480
            ..|..|..:|...|  ...|:...:....|.::     |..|.......|.:..::::::..:..
Zfish   631 EFFSPVGYNRSLQSGKKAGGSKFTIGKSIWLLW-----ALVFNNSVPVENPKGTTSKIMVLVWAF 690

  Fly   481 FTIIITSCYTGSIIAFVTLPAFPDTVDSVLDLLGLF---------FRVGTLNNGGWETWFQNS-- 534
            |.:|..:.||.::.||:....:.|||..:.|  ..|         .:.||:.||..|...:::
Zfish   691 FAVIFLASYTANLAAFMIQEEYIDTVSGLSD--KKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYP 753

  Fly   535 ------------------THIPTSRL----YKK--MEFVGSVDEGI-------GNVTQSFFWNYA 568
                              :|:.|.:|    |..  :.::...|||.       |.|..:..:..|
Zfish   754 DMHQYMVKYNQKSVEDAISHLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGIA 818

  Fly   569 FLGS---KAQLEYLVQSNFSDENISRRSALHLSEEC----------------------------- 601
            .:.:   |..|:..:.....|:.|.....|.||..|
Zfish   819 LIKNSRWKRPLDLALLQLVGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMG 883

  Fly   602 -----FALFQIGFLFPRESVYKI----KIDSMILLAQ-------------QSGLIAKINNEVSWV 644
                 ||...:.:...|..:.|:    |:|.::..::             |.|....::......
Zfish   884 LSLLVFAWEHLVYWRLRHCMSKMGQSGKLDFLLAFSRGMYSCCSFEDETAQGGAKVTVSGHHHTA 948

  Fly   645 MQRSSSGRLLQASSSNSLREIIQEERQ 671
            |..:||..::.::.||....::|:::|
Zfish   949 MVPTSSSHVVTSAVSNPAIAMVQQQQQ 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir21a	NP_001097043.1	HisJ	287..>392	CDD:440596	21/132 (16%)
		Lig_chan	405..662	CDD:459656	60/363 (17%)
grin2db	XP_073782035.1	None