Protein Alignment HSPB1 and Hsp23

DIOPT Version :9

• Sequence 1: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Sequence 2: NP_001246694.1
• Gene: Hsp23 / 39077
• FlyBaseID: FBgn0001224
• Length: 186
• Species: Drosophila melanogaster
• Alignment Length: 131
• Identity: 54/131 - (41%)
• Similarity: 79/131 - (60%)
• Gaps: 9/131 - (6%)

Human    75 RALSRQL-----SSG-VSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGY 133
            |.|.:|:     ||| ||:|  ..|.::|.:||:||.|.||.||.:|..|.:.|.||||:|:||:
  Fly    47 RQLEKQVGASSGSSGAVSKI--GKDGFQVCMDVSHFKPSELVVKVQDNSVLVEGNHEEREDDHGF 109

Human   134 ISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPM-PKLATQSNEITIPVTFESRAQLGGPEAA 197
            |:|.|.|:|.||||.:..:|:|:||.:|.||::.|. |.:..:.||..:.:.....|.|...|..
  Fly   110 ITRHFVRRYALPPGYEADKVASTLSSDGVLTIKVPKPPAIEDKGNERIVQIQQVGPAHLNVKENP 174

Human   198 K 198
            |
  Fly   175 K 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		54/131 (41%)
		ACD_HspB1_like	84..169	CDD:107230	41/85 (48%)
Hsp23	NP_001246694.1	metazoan_ACD	67..145	CDD:107247	37/77 (48%)
		IbpA	<69..161	CDD:223149	41/91 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101545
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.720