Protein Alignment HSPB1 and CG4461

DIOPT Version :9

• Sequence 1: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Sequence 2: NP_648304.1
• Gene: CG4461 / 39074
• FlyBaseID: FBgn0035982
• Length: 200
• Species: Drosophila melanogaster
• Alignment Length: 172
• Identity: 49/172 - (28%)
• Similarity: 70/172 - (40%)
• Gaps: 49/172 - (28%)

Human    16 WDPFRDWY--PHSRLFDQAFGLPRL-------------PEEWSQWLGGSSWPGYVRPLPPAAIES 65
            ||..|.|:  ||:...|....|..|             |.||:..:   .|..|
  Fly    35 WDDSRLWWPSPHTSRSDLLRPLDELVSRRVRNQLIQSTPYEWAHPM---RWDNY----------- 85

Human    66 PAVAAPAYSRALSRQLSSGVSEIRHTADR-WRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQD 129
                   ||           .|..|..:: :|:.:||..|.|.::.|||.|..|.:.|.|..|.:
  Fly    86 -------YS-----------GERVHVDEKGFRIDIDVRQFHPHDIVVKTNDDYVIVQGNHNRRDE 132

Human   130 -EHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMP 170
             .:|.:.|.|.|||.||.|.:..:|.|.:|.:|.||::||.|
  Fly   133 GSNGLVERHFVRKYLLPRGYNANEVISDISSDGILTIKAPPP 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		35/103 (34%)
		ACD_HspB1_like	84..169	CDD:107230	31/86 (36%)
CG4461	NP_648304.1	metazoan_ACD	94..169	CDD:107247	27/74 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820