Protein Alignment HSPB1 and Hsp67Bc

DIOPT Version :9

• Sequence 1: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Sequence 2: NP_523994.1
• Gene: Hsp67Bc / 39071
• FlyBaseID: FBgn0001229
• Length: 199
• Species: Drosophila melanogaster
• Alignment Length: 137
• Identity: 49/137 - (35%)
• Similarity: 68/137 - (49%)
• Gaps: 15/137 - (10%)

Human    76 ALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTR 140
            ||||   .|.|   :....:.|.|||..|.|.|||||..:..:.:.||||||:|:||::||.|.|
  Fly    68 ALSR---GGAS---NKQGNFEVHLDVGLFQPGELTVKLVNECIVVEGKHEEREDDHGHVSRHFVR 126

Human   141 KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQL---------GGPEA 196
            :|.||...|...:.|:||.:|.|.:..|......:..|..||:.....:.|         .||.|
  Fly   127 RYPLPKEFDSDAIVSTLSEDGVLNITVPPLVSKEELKERIIPIKHVGPSDLFQNGNGHKEAGPAA 191

Human   197 AKSDETA 203
            :.|:..|
  Fly   192 SASEPEA 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		49/137 (36%)
		ACD_HspB1_like	84..169	CDD:107230	35/84 (42%)
Hsp67Bc	NP_523994.1	metazoan_ACD	75..154	CDD:107247	34/81 (42%)
		IbpA	<79..170	CDD:223149	37/90 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820