Protein Alignment HSPB1 and Hspb1

DIOPT Version :10

• Sequence 1: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Sequence 2: NP_114176.4
• Gene: Hspb1 / 24471
• RGDID: 61306
• Length: 206
• Species: Rattus norvegicus
• Alignment Length: 209
• Identity: 171/209 - (81%)
• Similarity: 186/209 - (88%)
• Gaps: 7/209 - (3%)

Human     1 MTERRVPFSLLRGPSWDPFRDWYP-HSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIE 64
            ||||||||||||.|||:||||||| ||||||||||:||.|:|||||...:.|||||||||.|..|
  Rat     1 MTERRVPFSLLRSPSWEPFRDWYPAHSRLFDQAFGVPRFPDEWSQWFSSAGWPGYVRPLPAATAE 65

Human    65 SPA---VAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEE 126
            .||   :||||:||||:|||||||||||.||||||||||||||||:|||||||:|||||||||||
  Rat    66 GPAAVTLAAPAFSRALNRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKEGVVEITGKHEE 130

Human   127 RQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQL 191
            |||||||||||||||||||||||||.||||||||||||||||:||..|||.|||||||||:|||:
  Rat   131 RQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQSAEITIPVTFEARAQI 195

Human   192 GGPEAAKSDETAAK 205
            ||||   |:::.||
  Rat   196 GGPE---SEQSGAK 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		115/134 (86%)
		ACD_HspB1_like	84..169	CDD:107230	80/84 (95%)
Hspb1	NP_114176.4	Interaction with TGFB1I1. /evidence=ECO:0000269|PubMed:11546764	74..206		115/134 (86%)
		ACD_HspB1_like	88..173	CDD:107230	80/84 (95%)