Protein Alignment HSPB1 and hsp-12.2

DIOPT Version :10

• Sequence 1: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Sequence 2: NP_498776.1
• Gene: hsp-12.2 / 176148
• WormBaseID: WBGene00002011
• Length: 110
• Species: Caenorhabditis elegans
• Alignment Length: 107
• Identity: 41/107 - (38%)
• Similarity: 58/107 - (54%)
• Gaps: 2/107 - (1%)

Human    61 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHE 125
            :|||..|.||..:...|  |.:.||.::.:|.:::.|.|||..|.|.|:.||.....:.|..:||
 Worm     2 SAIEVTADAASTWDWPL--QHNDGVVKVHNTKEKFEVGLDVQFFTPKEIEVKVSGQELLIHCRHE 64

Human   126 ERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEA 167
            .|.|.||.::|...|.|.||..||.:.|.|.|:..|.||:.|
 Worm    65 TRSDNHGTVAREINRAYKLPDDVDVSTVKSHLATRGVLTITA 106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		36/98 (37%)
		ACD_HspB1_like	84..169	CDD:107230	33/84 (39%)
hsp-12.2	NP_498776.1	metazoan_ACD	26..108	CDD:107247	31/81 (38%)