DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda4 and chia.2

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	346	Identity:	74/346 - (21%)
Similarity:	106/346 - (30%)	Gaps:	119/346 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 SISQQQGLQDKGYEEWVGEMIGMREILRH--FANVSVNDVVGMRAPFLKPGRNTQ-YKVLEDFG- 255
            ::|..:|..|.|||        :.||.::  |.|:...|..|....|  .|.|:. |:..:|.|
Zfish   183 AVSAGKGTIDDGYE--------IAEIAKYLDFINIMTYDFHGTWERF--TGHNSPLYQGSKDEGD 237

  Fly   256 YIYDSSITVPPVPVPVWPYTLDYKISHECKSGTCP-----------SRTF-----------PGVW 298
            .:|               :..||.:.:...:|| |           .|||           |...
Zfish   238 LVY---------------FNTDYAMRYWRDNGT-PVEKLRMGFATYGRTFRLTSSDTSVGAPASG 286

  Fly   299 EVPLNTHYVEGYEGGHCPYLDQCVLHNLDEEEVFQWLQEDFSRYYEQNKAPYMMPFHTNW--FQT 361
            .....|:   ..|.|...|.:.|   ...|....||:        :..|.||... ::.|  |.|
Zfish   287 PASAGTY---TREAGFWSYYEIC---GFLEGTTVQWI--------DDQKVPYATK-NSEWVGFDT 336

  Fly   362 KPLENGLHKFLD---------WALELPDVYILTVTQMLQYVTDP--KELRDVSQIESWKCDKSVS 415
            |.......::|.         |||:|.|.    ..|.......|  ..||::..||       :.
Zfish   337 KESYETKVRYLKDKKFGGAFVWALDLDDF----AGQFCGQGNHPLMGHLRNLLDIE-------LP 390

  Fly   416 VAPKPCNIWQTCALPFKI---PEQNLTDTRYMETCREC------------PNVYPWLGDAGGTGI 465
            ..|.|     |.|.|.:.   |....|.|.:......|            ||.|        ...
Zfish   391 PLPPP-----TTAKPGQSTTRPTTTTTTTTHAPGPGFCNGKPDGLYAHPDPNKY--------YSC 442

  Fly   466 AGRDNYIFAGGENPEEEDSAK 486
            ||...|:...|...|.::|.|
Zfish   443 AGGQTYVDNCGAGTEFDESCK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	50/237 (21%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	53/246 (22%)
		Glyco_18	24..363	CDD:214753	47/220 (21%)
		CBM_14	423..468	CDD:279884	11/49 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930