DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda4 and Cda5

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_722590.2	Gene:	Cda5 / 33158	FlyBaseID:	FBgn0051973	Length:	1998	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	161/402 - (40%)
Similarity:	228/402 - (56%)	Gaps:	17/402 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PSGLFFDDVQKFCTFKDEAKCGPLPTTPAPATEAPADTAQRCNTENCALPYCFCSKDGTQIPGDL 124
            |||......|:|..........|.|..|.|   .|..||.:|..:.|.||.|:|.  |..|||:|
  Fly  1599 PSGTIVSKAQEFVDIYRYPPSRPDPIYPQP---MPDKTAAKCRKDVCLLPDCYCG--GRDIPGEL 1658

  Fly   125 EPEKIPQIIMLTFDGAVNLNNYQHYQKIFDGKRKNPNGCLIRGTFFMSHEYSNYQQIQHLGYYGH 189
            ..|.||||::||||.:||..|.|.|..:|:..|.|||||.|..||::|||:::|.|:|:|...||
  Fly  1659 PVESIPQIVLLTFDDSVNDLNKQLYTDLFEKGRVNPNGCPITATFYVSHEWTDYSQVQNLYADGH 1723

  Fly   190 EIGTESISQQQGLQDKGYEEWVGEMIGMREILRHFANVSVNDVVGMRAPFLKPGRNTQYKVLEDF 254
            |:.:.::|...| :....::|..|:.|.||||..:..|.::||.|||||||..|.|..||:|.|.
  Fly  1724 EMASHTVSHSFG-EQFSQKKWTREIAGQREILAAYGGVKMSDVRGMRAPFLSVGGNKMYKMLYDS 1787

  Fly   255 GYIYDSSITVPPVPVPVWPYTLDYKISHECKSGTCPSRTFPGVWEVPLNTHYVEGYEGGHCPYLD 319
            .:.||||:.|.....|.|||||||||.|:|....||:|::||||:||:...  :...||.|...|
  Fly  1788 NFTYDSSMPVYENRPPSWPYTLDYKIFHDCMIPPCPTRSYPGVWQVPMVMW--QDLNGGRCSMGD 1850

  Fly   320 QCVLHNLDEEEVFQWLQEDFSRYYEQNKAPYMMPFHTNWFQTKPLENGLHKFLDWALELPDVYIL 384
            .| .:..|.:.|.:.:.::|.|:|..|:||:.:.:|..||.....:.|..||||....:.||:|:
  Fly  1851 AC-SNPSDADGVTKMIMKNFERHYTTNRAPFGLFYHAAWFTQPHHKEGFIKFLDAINAMQDVWII 1914

  Fly   385 TVTQMLQYVTDPKELRDVSQIESWKCDKSVSVAPKPCNIWQTCALPFKIPEQNLTDTRYMETCRE 449
            |..|.||:|.||..:..::..:.::||  .|..||.||..:.|.|..|      :..|||:||:.
  Fly  1915 TNWQALQWVRDPTPISRINSFQPFQCD--YSDRPKRCNNPKVCNLWHK------SGVRYMKTCQP 1971

  Fly   450 CPNVYPWLGDAG 461
            ||::|||.|.:|
  Fly  1972 CPDIYPWTGKSG 1983

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884	5/19 (26%)
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	112/265 (42%)
Cda5	NP_722590.2	CBM_14	58..106	CDD:279884
Cda5	NP_722590.2	CE4_CDA_like_2	1664..1926	CDD:200597	112/265 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463795
Domainoid	1	1.000	121	1.000	Domainoid score	I3513
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060206at2759
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950