DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda4 and chia.6

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_955897.2	Gene:	chia.6 / 322420	ZFINID:	ZDB-GENE-030131-1140	Length:	480	Species:	Danio rerio

Alignment Length:	360	Identity:	68/360 - (18%)
Similarity:	110/360 - (30%)	Gaps:	129/360 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 GTQIPGDLEPEKIPQIIMLTFDGAVNLNNYQHYQ-------KIFDG-KRKNPN-------GCLIR 166
            |..:|.:::|.....:| ..|....|.|....|:       :.|:| |:.|||       |....
Zfish    38 GKYMPSNVDPHLCTHLI-YAFSIINNENKLTTYEWNDETLYQSFNGLKQSNPNLKTLLAVGGWNF 101

  Fly   167 GTFFMSHEYSNYQQIQHL-----------GYYGHEIG---------------------------- 192
            ||...|...|..|..|..           |:.|.::.
Zfish   102 GTTQFSSMVSTPQNRQTFIQSSITFLRTHGFDGLDLDWEYPGSRGSPPEDKQRFTLLCKELVEAY 166

  Fly   193 --------------TESISQQQGLQDKGYEEWVGEMIGMREILRH--FANVSVND-------VVG 234
                          |.:::..:|..|.|||        :.||.::  |.|:...|       |.|
Zfish   167 QAESAATGRPRLMLTAAVAAGKGNIDAGYE--------IAEIAKYLDFINIMTYDFHGSWESVTG 223

  Fly   235 MRAPFLKPGRNTQYKVL--EDFGYIY--DSSITVPPVPVPVWPYTLDYKISHECK------SGTC 289
            ..:|..:...:...|:.  .||...|  |....|..:.:....|...:::|....      ||..
Zfish   224 HNSPLYRGSGDIGDKIYYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFRLSSAVSGVGAPASGAA 288

  Fly   290 PSRTF---PGVWEVPLNTHYVEGYEGGHCPYLDQCVLHNLDEEEV------FQWLQEDFSRYYEQ 345
            .:.|:   .|.|..         ||  .|.:|.|..:..:.:::|      .:|:..|....| :
Zfish   289 SAGTYTREAGFWSY---------YE--ICTFLKQATVQQIVDQKVPYATKGQEWVGFDNMESY-K 341

  Fly   346 NKAPYMMPFHTNWFQTKPLENGLHKFLDWALELPD 380
            .|..|:.            |.|......|||:|.|
Zfish   342 TKVDYLK------------EKGFGGAFVWALDLDD 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	65/347 (19%)
chia.6	NP_955897.2	Glyco_18	22..363	CDD:214753	66/357 (18%)
		GH18_chitolectin_chitotriosidase	23..385	CDD:119351	68/360 (19%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930