DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cda4 and chil-11

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_500856.2	Gene:	chil-11 / 183470	WormBaseID:	WBGene00016665	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	413	Identity:	74/413 - (17%)
Similarity:	122/413 - (29%)	Gaps:	167/413 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 DLEPEKIPQIIMLTFD------GAVNLNNYQHYQKIFDGKRKNPNGCLIRGTFFMSHEYSNYQQI 181
            :.||:.|.:||.....      ..|.|:...|  .:|...|...||....|..|...::.|:|:
Worm     5 ETEPDVIKRIIGYYIQKESSEISTVGLSRLTH--AVFGSLRVQLNGTFEIGNAFSKRKFKNWQR- 66

  Fly   182 QHLGYYGHEIGTESISQQQGLQDKGYEEWVGEMIGMREILRHFANVSVNDVVGMRAPFLKP---- 242
                    .:...|.:.:..:.           ||..:.:...::|.:|  |..|..|::.
Worm    67 --------AVKNSSSNVKSMIS-----------IGRWDSVTQLSSVLLN--VKSRRMFIESIVDF 110

  Fly   243 ------------GRNTQYKVLEDFGYI--------------YDSSITVPPVPVPVWPYTLDYKIS 281
                        .|.....|..:|...              |..|||.|||.
Worm   111 LKEHQLDGIDLFWRWVPLAVQSEFCLFLEEVKIEFLNQEKQYILSITAPPVG------------- 162

  Fly   282 HECKSGTCPSRTFPGVWEVPLNTHYVEGYEGGHCPYLDQCVLHNLDEEEVFQWLQEDFSRYYEQN 346
                                     :|.||.|:            |.||:.:  :.||...|..|
Worm   163 -------------------------IENYEDGY------------DIEEIIE--RVDFVNVYSMN 188

  Fly   347 KAPYMMPFHTNW----FQTKPLENGL---HKF-LDWALELPDVYILTVTQMLQYVTDPKELRDV- 402
               |..|:...|    ..:.||..||   .|| :|:          |:...::|...|::...:
Worm   189 ---YAAPWSNQWGTPTGPSAPLYGGLDARRKFSVDY----------TMKYYIRYTRKPEKFNLII 240

  Fly   403 -SQIESWKCDKSVSVAPKP-CNIWQTCALPFKIPEQN--LTDTRYMETCRECPNVYPWLGDAGGT 463
             ..:..|   ::|..|.|| ..:::...|      ||  .....||..         |..::.|.
Worm   241 PFYVRHW---RNVENAIKPGIEVFRNVTL------QNNGAIGEVYMSR---------WTAESDGI 287

  Fly   464 GIAGRDNYIFAGGENPEEEDSAK 486
            .::           ||..:|:.|
Worm   288 ELS-----------NPSWDDTTK 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	54/309 (17%)
chil-11	NP_500856.2	Glyco_18	13..343	CDD:214753	71/405 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164239
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930