DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda4 and lmd-4

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_504862.2	Gene:	lmd-4 / 179121	WormBaseID:	WBGene00017233	Length:	2011	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	50/231 - (21%)
Similarity:	78/231 - (33%)	Gaps:	80/231 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 KGYEEWVGEMIGMREILRH--FANVSVND-----------VVGMRAP-FLKPGRNTQYKVLEDFG 255
            |||:        ::.||::  |.||...|           ..|..|| :....:....|:..||.
Worm  1653 KGYD--------LKGILKYADFINVMTYDYYGAWESKWGAYTGTPAPLYFGSLKGFSGKLNADFS 1709

  Fly   256 YIYDSSITVPP----VPVP----VWPYTLDYKISHECKSGTCPSRTFPGVWE--VPLNTHYVEGY 310
            ..:.:..|..|    :.||    .|...|.            |......:|.  .|.|..|..||
Worm  1710 MKFYACKTEKPSQLNMGVPFYGRYWKNVLG------------PIDKSDNMWRTAAPQNGKYEGGY 1762

  Fly   311 EGGHCPYLDQCVLHNLDEEEVFQWLQEDFSRYYEQNKAPYMMPFHTNWFQTKPLENGLHKFLDWA 375
            .|          ..||.:|   .| .:..:.::|:.|.||:|            .||..|||.:.
Worm  1763 VG----------WRNLAKE---GW-NKGSASWHEKTKTPYIM------------NNGAKKFLGFE 1801

  Fly   376 LELPDVYILTVTQMLQYVTDPKELRDVSQIESWKCD 411
            .|      .::.:.::|.||    |::..:..|..|
Worm  1802 NE------RSLKEKMKYATD----RNLGGLMIWALD 1827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	46/214 (21%)
lmd-4	NP_504862.2	LysM	25..65	CDD:197609
		LysM	79..120	CDD:197609
		LysM	142..185	CDD:197609
		LysM	209..250	CDD:197609
		LysM	270..313	CDD:197609
		LysM	334..377	CDD:197609
		LysM	401..444	CDD:197609
		LysM	469..509	CDD:197609
		LysM	550..590	CDD:197609
		LysM	635..678	CDD:197609
		LysM	710..750	CDD:197609
		LysM	760..802	CDD:197609
		LysM	876..919	CDD:197609
		Self-incomp_S1	1359..1433	CDD:283566
		Glyco_18	1480..1825	CDD:214753	48/227 (21%)
		GH18_chitinase-like	1481..1824	CDD:299167	48/226 (21%)
		ChtBD1_GH18_2	1873..1924	CDD:211315
		ChtBD1_GH18_2	1951..2002	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930