DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda4 and Chil3

DIOPT Version :9

Sequence 1:	NP_728468.1	Gene:	Cda4 / 33144	FlyBaseID:	FBgn0052499	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_034022.2	Gene:	Chil3 / 12655	MGIID:	1330860	Length:	398	Species:	Mus musculus

Alignment Length:	243	Identity:	49/243 - (20%)
Similarity:	80/243 - (32%)	Gaps:	96/243 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 KDGTQIPGDLEPEKIPQIIMLTFD-----GAVNLNNYQHYQKIFD-GKRKNPN-GCLIRGTFFMS 172
            |.|.:|| :|. :.:..|.::|:|     ......|...|:..:| ||..:.| ..:|  :::..
Mouse   192 KSGYKIP-ELS-QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSII--SYWKD 252

  Fly   173 HEYSNYQQIQHLGYYGHE----------IGTESIS--------QQQGL----------------- 202
            |..::.:.|.....|||.          ||..:||        .:.||
Mouse   253 HGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEV 317

  Fly   203 ----QDKGY----EEWVGEMIGMREILRHFANVSVNDVVGMRAPFLKPGRNTQYKVLEDFGYIYD 259
                |:..|    .||||     .:.:|.|.         ::|.:||                 |
Mouse   318 WDAPQEVPYAYQGNEWVG-----YDNVRSFK---------LKAQWLK-----------------D 351

  Fly   260 SSITVPPVPVPVWPYTLDYKISHECKSGTCPSRTFP--GVWEVPLNTH 305
            :::.    ...|||..:|     :.....|..|.||  ...:..||.|
Mouse   352 NNLG----GAVVWPLDMD-----DFSGSFCHQRHFPLTSTLKGDLNIH 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda4	NP_728468.1	CBM_14	33..80	CDD:279884
Cda4	NP_728468.1	CE4_CDA_like_1	130..396	CDD:200596	44/228 (19%)
Chil3	NP_034022.2	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	46/238 (19%)
		Glyco_18	26..365	CDD:214753	41/211 (19%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	70..71
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	97..100
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	210..213		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930