Protein Alignment CG17598 and PPM1B

DIOPT Version :10

• Sequence 1: NP_608468.1
• Gene: CG17598 / 33140
• FlyBaseID: FBgn0031194
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_002697.1
• Gene: PPM1B / 5495
• HGNCID: 9276
• Length: 479
• Species: Homo sapiens
• Alignment Length: 566
• Identity: 101/566 - (17%)
• Similarity: 188/566 - (33%)
• Gaps: 190/566 - (33%)

  Fly   134 YTYFGIFDGHAGYGAA-LAASHQFHHILHEKLVDCLELLLPRDADATNGGGEGNKLNPTFPHPIY 197
            :::|.::|||||...| ..::|...||             ..:.|....|..|:.|..:.
Human    53 WSFFAVYDGHAGSRVANYCSTHLLEHI-------------TTNEDFRAAGKSGSALELSV----- 99

  Fly   198 FQRRVTKDELIIGALESAFFNMDSLIA--QDCDRYRDAGGCTACVSLFIDGK-MYVANAGDSRAV 259
                    |.:...:.:.|..:|..:.  .|.....|..|.|| |.:.|..| :|..|.||||||
Human   100 --------ENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTA-VGVMISPKHIYFINCGDSRAV 155

  Fly   260 LCQRRATPERPQTNTDSGIEPDPLEASCYPVPFSADHTPETERERLLNVARLKPHLMGKHYVAME 324
            |.:....                    |:.   :.||.|...||
Human   156 LYRNGQV--------------------CFS---TQDHKPCNPRE--------------------- 176

  Fly   325 YAKRPHIKDMGQRILCRQGTMRGWTYKTLTMEDLCMPVVNGEGKRSRLLGTLGVTRGFGDHELLA 389
               :..|::.|..::.:                             |:.|:|.|:|..||::...
Human   177 ---KERIQNAGGSVMIQ-----------------------------RVNGSLAVSRALGDYDYKC 209

  Fly   390 INTGIQIKPFLTPHPDVRQRDLTQVVSIPDEDNRDGDYGVLVMATDGLWDVSENDAVSRTVFQTL 454
            ::.....:..::|.|:|.:      :...:||.      .:::|.||:|||..|:.:...|
Human   210 VDGKGPTEQLVSPEPEVYE------ILRAEEDE------FIILACDGIWDVMSNEELCEYV---- 258

  Fly   455 SKYSTEKHRYTMVAQELVARARGKINDS----GHWRLADSKAAATVDDISVIVIPVC-----QYY 510
                               ::|.:::|.    .:|.:.......:.|::|:::  ||     :..
Human   259 -------------------KSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVL--VCFSNAPKVS 302

  Fly   511 KEHVEWTQNYKRDLEHRRRQAQAHMAQE-------------AVNVLN----GVIAEEAHVVE--- 555
            .|.|:......:.||.|..:......:|             |.|:.|    |.:|.:.:|:|
Human   303 DEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVY 367

  Fly   556 ----EEEEGEVVVHEARTSHNQTKVPRRL-------DGTLDETLVVELTPSLEQVHIQNADSAEG 609
                ...|.:....||..|.:|.|:...|       .|...: |:.|:..|.....::..:|...
Human   368 SRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQ-LLEEMLTSYRLAKVEGEESPAE 431

  Fly   610 ESSKENVNDKDKEASTTRQQSQQQQQQ-----QQQQQQKGRKGKGK 650
            .::....::.|.....|.|:|..:.:.     ....:..|.|..|:
Human   432 PAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGE 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17598	NP_608468.1	PP2Cc	98..506	CDD:238083	67/379 (18%)
PPM1B	NP_002697.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		PP2Cc	23..295	CDD:238083	68/381 (18%)
		PP2C_C	289..368	CDD:429684	16/80 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..479		8/55 (15%)