Protein Alignment CG17598 and PPM1N

DIOPT Version :10

• Sequence 1: NP_608468.1
• Gene: CG17598 / 33140
• FlyBaseID: FBgn0031194
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_047294180.1
• Gene: PPM1N / 147699
• HGNCID: 26845
• Length: 448
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 80/332 - (24%)
• Similarity: 106/332 - (31%)
• Gaps: 135/332 - (40%)

  Fly   130 PDLP--YTYFGIFDGHAGYGAA-LAASHQFHHILHEKLVDCLELLLPRDADATNGGGEGNKLNPT 191
            |.||  :..|.:.|||.|..|| ..|.|...|:|.|                         |.|.
Human    90 PGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQE-------------------------LGPE 129

  Fly   192 FPHPIYFQRRVTKDELIIGALESAFFNMDSLIAQDCDRYRDAGGCTACVSLFIDGKMYVANAGDS 256
            ...|          |.:..||..||.:.|..:.....|. :.|||||.|.|.....:|:|:.|||
Human   130 PSEP----------EGVREALRRAFLSADERLRSLWPRV-ETGGCTAVVLLVSPRFLYLAHCGDS 183

  Fly   257 RAVLCQRRATPERPQTNTDSGIEPDPLEASCYPVPFSA-DHTPETERERLLNVARLKPHLMGKHY 320
            ||||.:..|                        |.||. ||.|...|||
Human   184 RAVLSRAGA------------------------VAFSTEDHRPLRPRER---------------- 208

  Fly   321 VAMEYAKRPHIKDMGQRILCRQGTMRGWTYKTLTMEDLCMPVVNGEGKRSRLLGTLGVTRGFGDH 385
                           :||....||:|                      |.|:.|:|.|:|..||
Human   209 ---------------ERIHAAGGTIR----------------------RRRVEGSLAVSRALGD- 235

  Fly   386 ELLAINTGIQIKPFLTPHPDVRQRDLTQVVSIPDED---NRDGDYGVLVMATDGLWDVSENDAVS 447
                         |.......|..:| |:||...|.   .|..:...:::|:||:||.....|::
Human   236 -------------FTYKEAPGRPPEL-QLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALA 286

  Fly   448 RTVFQTL 454
            ..|...|
Human   287 GLVASRL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17598	NP_608468.1	PP2Cc	98..506	CDD:238083	80/332 (24%)
PPM1N	XP_047294180.1	PP2Cc	66..326	CDD:238083	80/332 (24%)
		PP2C_C	320..389	CDD:429684