Protein Alignment CG17598 and PPM1M

DIOPT Version :10

• Sequence 1: NP_608468.1
• Gene: CG17598 / 33140
• FlyBaseID: FBgn0031194
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_653242.3
• Gene: PPM1M / 132160
• HGNCID: 26506
• Length: 459
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 170/482 - (35%)
• Similarity: 257/482 - (53%)
• Gaps: 70/482 - (14%)

  Fly    50 GQPMP---------DKFPYARPPFLQ--LLTPDELRASADHNVRPIIVPRDINLLPWGTGYAECV 103
            |:|:|         ...||.||.||:  ..:|....||...:.||:..|.....|||..||||.:
Human    13 GEPLPAPRPPGPHASPVPYRRPRFLRGSSSSPGAADASRRPDSRPVRSPARGRTLPWNAGYAEII 77

  Fly   104 NSGKSEWNEDQ---GAFC-RQVLSDPEHKH----PD--LPYTYFGIFDGHAGYGAALAASHQFHH 158
            |:.|||:||||   |..| |:.....|.:.    |:  |...|:.:||||.|..||:.|::..|.
Human    78 NAEKSEFNEDQAACGKLCIRRCEFGAEEEWLTLCPEEFLTGHYWALFDGHGGPAAAILAANTLHS 142

  Fly   159 ILHEKLVDCLELLL----PRDADATNGGGEGNKLNPTFPHPIYFQRRVTKDELIIGALESAFFNM 219
            .|..:|...:|.|:    |...:       |..:.|:.|..:. ::.:..::|:||||||||...
Human   143 CLRRQLEAVVEGLVATQPPMHLN-------GRCICPSDPQFVE-EKGIRAEDLVIGALESAFQEC 199

  Fly   220 DSLIAQDCDRYRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPERPQTNTDSGIEPDPLE 284
            |.:|.::.:.....|||||.|::.:.||:|:||||||||:|.:|                 |.:.
Human   200 DEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRR-----------------DEIR 247

  Fly   285 ASCYPVPFSADHTPETERERLLNVARLKPHLMGKHYVAMEYAKRPHIKDMGQRILCRQGTMRGWT 349
                  |.|.:.||||||:|:..:|.:.|.|:...:..:|:.:|....|:||::|.|...|.||:
Human   248 ------PLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWS 306

  Fly   350 YKTLTMEDLCMPVVNGEGKRSRLLGTLGVTRGFGDHELLAINTGIQIKPFLTPHPDVRQRDLTQV 414
            ||.:...||..|:::|:|:::||||||.|:||.|||:|..::|.||:||||...|.|...|:.|
Human   307 YKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQ- 370

  Fly   415 VSIPDEDNRDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKYSTEKHRYTMVAQELVARARGKI 479
            :.:.::|       |:||||||||||..|:.|:..|...|.....:.||::.:||.|:...:||
Human   371 LELQEDD-------VVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGK- 427

  Fly   480 NDSGHWRLADSKAAATVDDISVIVIPV 506
            .||     ...:...:.||:||.|||:
Human   428 EDS-----LTEEGQVSYDDVSVFVIPL 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17598	NP_608468.1	PP2Cc	98..506	CDD:238083	151/421 (36%)
PPM1M	NP_653242.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64		15/50 (30%)
		PP2Cc	118..449	CDD:238083	133/375 (35%)