Protein Alignment S6kII and TPK3

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 356
• Identity: 137/356 - (38%)
• Similarity: 199/356 - (55%)
• Gaps: 34/356 - (9%)

  Fly   144 DSESQGGVETGGRREGATGRSA---------PDLEDTEPLYETENEFELKEVIKEGHDKADPSQF 199
            :..|...||..||..|.....|         |.|:    ..:|..::.|             |.|
Yeast    41 ECSSNTPVEINGRNSGKLKEEASAGICLVKKPMLQ----YRDTSGKYSL-------------SDF 88

  Fly   200 ELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATL-KVKDRVRSTNERKILADVGHAFIVR 263
            ::||.||.||||:|.|:|   ....|..||:|.|||.|: |:|....:.:||::|:.|.|.||:|
Yeast    89 QILRTLGTGSFGRVHLIR---SNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIR 150

  Fly   264 LHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPE 328
            :...||...::::::|::.||:||:.|.|...|.....|||.||:.||:.:||:..|||||||||
Yeast   151 MWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPE 215

  Fly   329 NILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLT 393
            |||||::|||.:||||.:|...|  .||:.|||.:|:|||:|:.|.::.:.||||||||:||||.
Yeast   216 NILLDKNGHIKITDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA 278

  Fly   394 GNLPFHGQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFA 458
            |..||:.....:|...||.::|..|....|:||.||:.|..|:...|||....|..|:|.|.:|.
Yeast   279 GYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFN 343

  Fly   459 TIDWVRLERKQVRPPFIPAV--SRDDAFYFD 487
            .:.|.:|..:.:..|:.|.:  .:.|...||
Yeast   344 EVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	123/288 (43%)
		STKc_RSK_C	567..883	CDD:270993
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	126/294 (43%)