Protein Alignment S6kII and PDK1

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_568138.1
• Gene: PDK1 / 830330
• AraportID: AT5G04510
• Length: 491
• Species: Arabidopsis thaliana
• Alignment Length: 514
• Identity: 133/514 - (25%)
• Similarity: 228/514 - (44%)
• Gaps: 94/514 - (18%)

  Fly   178 ENEFELKEVI------------------KEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDA 224
            |.||:.|.|:                  |...:......||..::.|.||:.||...:|   |:.
plant     5 EKEFDSKLVLQGNSSNGANVSRSKSFSFKAPQENFTSHDFEFGKIYGVGSYSKVVRAKK---KET 66

  Fly   225 GTLYAMKVLKKATLKVKDRVRSTN-ERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFT 288
            ||:||:|::.|..:..:::..... ||.:|..:.|..|::|::.||....||:.|:...||:||.
plant    67 GTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFD 131

  Fly   289 RLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGS 353
            :::::...:|::.:||.||:..|:.::|::|:|:||:||||:||...|||.:.||| |.:|:..|
plant   132 QITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFG-SVKPMQDS 195

  Fly   354 ------------KTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQET 406
                        |..:|.||..|:.||::|.....|..|.|:.|..:|:||:|..||...:....
plant   196 QITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLI 260

  Fly   407 MNQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVR 471
            ..:|:...:..|.:.|..|:.|:..|....|..|.|||::|.:.:|.|.||..:||..| |.|..
plant   261 FQRIIARDIKFPNHFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNL-RSQTP 324

  Fly   472 PPFIPAVSRDDAFYFDVEYTSKSPR--DSPGGPISASAHEIFRGFSFVAPVLLEGQCAGSNMCST 534
            |...|          |....:.||.  |:.|.|.:.: |                  .|.::.:.
plant   325 PKLAP----------DPASQTASPERDDTHGSPWNLT-H------------------IGDSLATQ 360

  Fly   535 SASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGT--FSVCRLCEHRASKKHYAV- 596
            :..  ||..|..:...|:...|..:  .:|.:.:....|.|...  .|..:..:...|||...:
plant   361 NEG--HSAPPTSSESSGSITRLASI--DSFDSRWQQFLEPGESVLMISAVKKLQKITSKKVQLIL 421

  Fly   597 ------------KVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSV--YEDA 641
                        |::.|..:..:..|      .::.:::...:|..|.|...|  :|||
plant   422 TNKPKLIYVDPSKLVVKGNIIWSDNS------NDLNVVVTSPSHFKICTPKKVLSFEDA 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	102/328 (31%)
		STKc_RSK_C	567..883	CDD:270993	16/92 (17%)
PDK1	NP_568138.1	STKc_PDK1	42..311	CDD:270733	88/272 (32%)
		PH_3	388..490	CDD:434057	16/93 (17%)