Protein Alignment S6kII and sgk1

DIOPT Version :9

• Sequence 1: NP_001259779.1
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_012818527.1
• Gene: sgk1 / 594981
• XenbaseID: XB-GENE-1003518
• Length: 434
• Species: Xenopus tropicalis
• Alignment Length: 473
• Identity: 171/473 - (36%)
• Similarity: 250/473 - (52%)
• Gaps: 65/473 - (13%)

  Fly    69 TEDDESGGGNSGVTSS-------VTTVTSSQRRQQLQQVQQQSALQAALEQHHISPTADLDSARK 126
            |...|:..|::.:|.|       :......|||..|....|:.|..::....|....:.|:
 Frog     2 TVKTETAAGSNTLTYSKMRGMVALLIAFMKQRRMGLNDFIQKIATNSSYACKHSEVQSILN---- 62

  Fly   127 RPTHRTLCPP--PELMELSDSESQGGVETGGRREGATGRSAPDLEDTEPLYETENEFELKEVIKE 189
                  :.||  |||:.                           |::.|......:..|.   ..
 Frog    63 ------ISPPQEPELLN---------------------------ENSSPPPSPSQQINLG---PS 91

  Fly   190 GHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVL-KKATLKVKDRVRSTNERKI- 252
            .:..|.||.|:.|:::|:||||||.|.|....:   ..||:||| |||.||.|:.....:||.:
 Frog    92 SNPHAKPSDFQFLKIIGKGSFGKVLLARHNADE---KFYAVKVLQKKAILKKKEEKHIMSERNVL 153

  Fly   253 LADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHT 317
            |.:|.|.|:|.||::|||..:||.|||::.||:||..|.:|..|.|...:||.||:|.|:.:||:
 Frog   154 LKNVKHPFLVGLHFSFQTTSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHS 218

  Fly   318 LGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYS-FCGTVEYMAPEIVNRKGHDFAADW 381
            |.|:||||||||||||..|||.||||||.|:.::.:.|.| ||||.||:|||:::::.:|...||
 Frog   219 LNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDW 283

  Fly   382 WSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQ 446
            |..|.::||||.|..||:.:...|..:.||...|.:..|::..|::||..|.:::...|:|| ..
 Frog   284 WCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGA-KN 347

  Fly   447 GILDIKAHCFFATIDWVRLERKQVRPPFIPAVS-RDDAFYFDVEYTSKSPRDSPG-GP----ISA 505
            ..::||.|.||:.|:|..|..|::.|||.|.|| ..|..:||.|:|.:...:|.| .|    |:|
 Frog   348 DFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITA 412

  Fly   506 S---AHEIFRGFSFVAPV 520
            |   |.|.|.|||:..|:
 Frog   413 SIKEAAEAFMGFSYAPPM 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_001259779.1	S_TKc	199..457	CDD:214567	117/260 (45%)
		STKc_RSK_N	203..517	CDD:270734	144/325 (44%)
		STKc_RSK_C	567..883	CDD:270993
		S_TKc	568..834	CDD:214567
sgk1	XP_012818527.1	STKc_SGK1	93..431	CDD:270753	150/342 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940