Protein Alignment S6kII and Pka-C2

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 320
• Identity: 114/320 - (35%)
• Similarity: 179/320 - (55%)
• Gaps: 24/320 - (7%)

  Fly   204 VLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATL-KVKDRVRSTNERKILADVGHAFIVRLHYA 267
            |||.||||.|.|||:..||:   .||.|::.|..| ::|......||:.:|......|::.|..:
  Fly    50 VLGNGSFGTVMLVREKSGKN---YYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDS 111

  Fly   268 FQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILL 332
            .:....|||||..:.||:||:...:...|.|:..:||.|::|||:.::|.:.::|||||||||||
  Fly   112 TKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILL 176

  Fly   333 DEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLP 397
            |:.|:|.:||||.:|: :|| :|.:.|||.||:|||||..:.::.:.|||:||:|:||.:.|..|
  Fly   177 DQRGYIKITDFGFTKR-VDG-RTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSP 239

  Fly   398 FHGQTRQETM--NQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATI 460
            |....|...:  ::|......||...:.:.:||:.:|.:.:...|||....|..|:|:|.:|..:
  Fly   240 FAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGV 304

  Fly   461 DWVRLERKQVRPPFIPAV------SRDDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGF 514
            ||..:..::|..|:.|.:      |..:.|.|...|.|:..|..          |:|..|
  Fly   305 DWFGILNQEVTAPYQPTISGAEDLSNFENFEFKDRYKSRINRHP----------ELFANF 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	114/320 (36%)
		STKc_RSK_C	567..883	CDD:270993
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	106/288 (37%)