Protein Alignment S6kII and sgk1

DIOPT Version :9

• Sequence 1: NP_001259779.1
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_005162356.1
• Gene: sgk1 / 324140
• ZFINID: ZDB-GENE-030131-2860
• Length: 598
• Species: Danio rerio
• Alignment Length: 497
• Identity: 180/497 - (36%)
• Similarity: 251/497 - (50%)
• Gaps: 87/497 - (17%)

  Fly    44 QLRQRMQITSSGCSSLAVTPMEHTPTEDDESGGGNSGVTSSVTTVTSSQRRQQLQQVQQQSALQA 108
            |.|||.|         |:....|...|.|        ...|..|....||:..|....|:.:..:
Zfish   166 QPRQRTQ---------AMDLYYHGDPESD--------YCCSSDTTFMKQRKMGLNDFIQKLSANS 213

  Fly   109 ALEQH-------HISPTADLDSARKRPTHRTLCPPPELMELSDSESQGGVETGGRREGATGRSAP 166
            ...:|       :::|..|::.....|:     |||       |.|| .:..|           |
Zfish   214 YACKHPEVQSILNLTPPQDVELMNSNPS-----PPP-------SPSQ-QINLG-----------P 254

  Fly   167 DLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMK 231
            ....|                      |.||.|:.|:|:|:||||||.|.|.   :.....||:|
Zfish   255 SSNPT----------------------AKPSDFDFLKVIGKGSFGKVLLARH---RSDEKFYAVK 294

  Fly   232 VL-KKATLKVKDRVRSTNERKI-LADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEV 294
            || |||.||.|:.....:||.: |.:|.|.|:|.|||:|||..|||.:||::.||:||..|.:|.
Zfish   295 VLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRER 359

  Fly   295 MFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYS-F 358
            .|.|...:||.||:|.|:.:||:|.|:||||||||||||..|||.||||||.|:.::.:.|.| |
Zfish   360 CFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTF 424

  Fly   359 CGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSP 423
            |||.||:|||:::::.:|...|||..|.::||||.|..||:.:...|..:.||...|.:..|:|.
Zfish   425 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISN 489

  Fly   424 EAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVS-RDDAFYFD 487
            .|:.||..|.:::...|||. .....:||.|.||:.|:|..|..|::.|||.|.|: .:|..:||
Zfish   490 AARHLLEGLLQKDRTKRLGF-TDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFD 553

  Fly   488 VEYTSKSPRDSPG-GPISA-------SAHEIFRGFSFVAPVL 521
            .|:|.:...:|.| .|.||       .|.|.|.|||: ||.:
Zfish   554 PEFTDEPVPNSIGCSPDSALVTSSITEATEAFLGFSY-APAM 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_001259779.1	S_TKc	199..457	CDD:214567	120/260 (46%)
		STKc_RSK_N	203..517	CDD:270734	145/325 (45%)
		STKc_RSK_C	567..883	CDD:270993
		S_TKc	568..834	CDD:214567
sgk1	XP_005162356.1	STKc_SGK1	257..595	CDD:270753	153/365 (42%)
		S_TKc	265..522	CDD:214567	120/260 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940