Protein Alignment S6kII and Rps6kc1

DIOPT Version :9

• Sequence 1: NP_001259779.1
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_006250521.1
• Gene: Rps6kc1 / 289342
• RGDID: 1306578
• Length: 1045
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 145/617 - (23%)
• Similarity: 222/617 - (35%)
• Gaps: 190/617 - (30%)

  Fly     1 MPLADSQKDLRQQPQQQQQQQHVSS---TSSSNNAEQQCSSSGLGL---QLRQRMQITS------ 53
            :||..|.....|....|:.....||   ..|.:::|::|::..|.|   ..::::.:||
  Rat   469 LPLKTSLTPSSQDDSNQEDDGQDSSPKWPDSGSSSEEECTAGYLTLCNEYGQEKLDLTSLNEESV 533

  Fly    54 -----SGCSSLAVTPMEHTPTEDDESGG-------GNSGVTSSVTTVTSSQRRQQLQQVQQQSAL 106
                 ....|.||.....:.|.|..|..       |:.|:.:..:..||...|:......:...:
  Rat   534 MQPEGENADSQAVRSFPASLTADSASPSTQLKFFPGDEGLEAVCSPRTSDSLRRSKNSPMEFFRI 598

  Fly   107 QAALEQHHISPTADLDSARKRPTHRTLCPPP--ELMELSD----------------SESQGGVET 153
            .:   :...|....|||..|.   .:|.|.|  .|..|.|                ||:|..:..
  Rat   599 DS---KDSTSELLGLDSGEKL---HSLKPEPLKALFTLEDGDSPSQSFDAGKSQGESEAQDSISR 657

  Fly   154 GGR--------REGAT--------GRSAPDL-----EDTEPLYETE------------NEFELKE 185
            |..        :|.|:        ||  |||     .:.:|..||.            ...|..:
  Rat   658 GSDDSVPVISFKEAASEDVCSAEEGR--PDLLVNLPGELQPTKETSAVDPTKFSQASIGRLEAPD 720

  Fly   186 VI-------------KEGHDK-ADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKV---- 232
            |:             :||.:: :.|::|....|..|.|          ...|.|.|:...|
  Rat   721 VLCLRLSSEQCHDLGQEGPEELSHPTEFRPGGVTPERS----------AQADLGVLFTATVDHSS 775

  Fly   233 ----------------------------LKKATLKVKDRVRSTNERKILADVGHAFIVRLHYAFQ 269
                                        |:::...:........|.....|...:..|.|   |.
  Rat   776 SQDQFLFSSLHSESDRLGQVEGAVTSQDLQESLFHIASPCSGAKEDSAHTDTATSEEVLL---FT 837

  Fly   270 TPGK-------------------LYLILDFLRGGDLFTRL--SKEVMFTEEDVKFYLAELALAMN 313
            .|.|                   ::.|.:     ||..||  |..:...|..::.:.||:.:|::
  Rat   838 EPSKEGDSEAKVRSVGAGGAEKEVHQIFE-----DLDQRLAVSARLFIPEGCIQRWAAEMVVALD 897

  Fly   314 HLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVE----YMAPEIVNRKG 374
            .||..||:.|||.|.||||::.|||.||.|.      ..|:....|.:..    |.|||:.....
  Rat   898 ALHREGIVCRDLNPNNILLNDGGHIQLTYFS------RWSEVEDLCDSDAIARMYCAPEVGAVTE 956

  Fly   375 HDFAADWWSFGVLMYEMLTGN--LPFH--GQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKR 435
            ...|.||||.|.:::|:|||.  :..|  |.....|:|        ||:.:|.||:||::.|.:.
  Rat   957 ETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLN--------MPDCVSEEARSLIQQLLQF 1013

  Fly   436 NPQNRLGAGAQGILDIKAHCFFATIDWVRLER 467
            ||..|||||..|:.|||:|.||..:||..|.|
  Rat  1014 NPMERLGAGVAGVEDIKSHPFFTPVDWAELTR 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_001259779.1	S_TKc	199..457	CDD:214567	84/318 (26%)
		STKc_RSK_N	203..517	CDD:270734	89/326 (27%)
		STKc_RSK_C	567..883	CDD:270993
		S_TKc	568..834	CDD:214567
Rps6kc1	XP_006250521.1	PX_RPK118_like	11..128	CDD:132820
		MIT_SNX15	237..305	CDD:239140
		PKc_like	334..>420	CDD:304357
		STKc_RPK118_like	<858..1035	CDD:270728	68/195 (35%)
		S_TKc	<867..1035	CDD:214567	67/181 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0603
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900