Protein Alignment S6kII and Prkaca

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001094392.1
• Gene: Prkaca / 25636
• RGDID: 3389
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 341
• Identity: 125/341 - (36%)
• Similarity: 201/341 - (58%)
• Gaps: 8/341 - (2%)

  Fly   160 ATGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDA 224
            |..:...:.|..:.......|..||:......:.|....|:.::.||.||||:|.||:.   |::
  Rat     5 AAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDHFDRIKTLGTGSFGRVMLVKH---KES 66

  Fly   225 GTLYAMKVL-KKATLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFT 288
            |..||||:| |:..:|:|....:.||::||..|...|:|:|.::|:....||::::::.||::|:
  Rat    67 GNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131

  Fly   289 RLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGS 353
            .|.:...|:|...:||.|::.|...:||:|.:|||||||||:|:|:.|:|.:||||.:|: :.|
  Rat   132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKG- 194

  Fly   354 KTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMP 418
            :|::.|||.||:||||:..||::.|.|||:.|||:|||..|..||......:...:|:..|:..|
  Rat   195 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259

  Fly   419 ENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAV-SRDD 482
            .:.|.:.:.|||.|.:.:...|.|....|:.|||.|.:|||.||:.:.:::|..||||.. ...|
  Rat   260 SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGD 324

  Fly   483 AFYFDVEYTSKSPRDS 498
            ...|| :|..:..|.|
  Rat   325 TSNFD-DYEEEEIRVS 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	118/298 (40%)
		STKc_RSK_C	567..883	CDD:270993
Prkaca	NP_001094392.1	STKc_PKA	42..331	CDD:271111	116/294 (39%)