Protein Alignment S6kII and Rps6kl1

DIOPT Version :9

• Sequence 1: NP_001259779.1
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001351244.1
• Gene: Rps6kl1 / 238323
• MGIID: 2443413
• Length: 545
• Species: Mus musculus
• Alignment Length: 459
• Identity: 120/459 - (26%)
• Similarity: 171/459 - (37%)
• Gaps: 160/459 - (34%)

  Fly    20 QQHVSSTSSSNNAEQQCSSSGLGLQLRQRMQITSSGCSSLAVTPMEHTPTEDDESGGGNSGVTSS 84
            |.|...:..::.:.|:.|.:    ||..|:.:         :||.|.||..
Mouse   232 QDHFQYSGLNSGSVQEKSQA----QLSTRLSL---------MTPAELTPGH-------------- 269

  Fly    85 VTTVTSSQRRQQLQQVQQQSALQAALEQHHISPTADLDSARKRPTHRTLCPPPELMELSDSESQG 149
                |..|.|..::..:...:|..||:   :...||.:.: .||:......|.| .....|.||
Mouse   270 ----TLRQNRIPMEPPRTSQSLPPALQ---LQKEADAEPS-SRPSAVFSSDPTE-APCGHSHSQ- 324

  Fly   150 GVETGGRREGATGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVF 214
                 .||.|.:...||    |:.|:          .::||.|          |||  |::|
Mouse   325 -----VRRAGQSSNPAP----TQRLH----------WVREGAD----------RVL--GAYG--- 355

  Fly   215 LVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTN----ERKILADVGHAFIVRLHYAFQTPGKLY 275
                                        |.|..|    .|..|.....|:.:|
Mouse   356 ----------------------------RGRGRNPPSANRASLGSGRAAWSLR------------ 380

  Fly   276 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDE-HGHIA 339
                                  |..||.:.||:.||:..||..|::.|||.|:|:|||: .|||.
Mouse   381 ----------------------EGQVKQWAAEMLLALEALHQQGVLCRDLNPQNLLLDQAEGHIQ 423

  Fly   340 LTDFG--------LSKQPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNL 396
            ||.||        .|::.:|       |   .|.|||:........|.||||:|.|:||:|||
Mouse   424 LTYFGQWSEVEPRCSQEAVD-------C---LYSAPEVGGISELTEACDWWSYGSLLYELLTG-- 476

  Fly   397 PFHGQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATID 461
              ...::.........::|.:||.||..|.|||..|.:..||.|||||..|...:|:|.||:||.
Mouse   477 --MALSQSHPSGFQAHTQLQLPEWLSHPAASLLTELLQFEPQRRLGAGGGGTSRLKSHPFFSTIQ 539

  Fly   462 WVRL 465
            |.||
Mouse   540 WSRL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_001259779.1	S_TKc	199..457	CDD:214567	76/270 (28%)
		STKc_RSK_N	203..517	CDD:270734	83/276 (30%)
		STKc_RSK_C	567..883	CDD:270993
		S_TKc	568..834	CDD:214567
Rps6kl1	NP_001351244.1	MIT_SNX15	48..122	CDD:239140
		STKc_RPK118_like	148..535	CDD:270728	113/449 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..344		26/124 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..372		6/49 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0603
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900