Protein Alignment S6kII and STK32A

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001274669.1
• Gene: STK32A / 202374
• HGNCID: 28317
• Length: 407
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 111/322 - (34%)
• Similarity: 177/322 - (54%)
• Gaps: 17/322 - (5%)

  Fly   184 KEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRST- 247
            |..:.:.::..:...||:||.:|:||||||.:|:|   .|...:||||.:.|.....::.||:.
Human     8 KPPVFDENEDVNFDHFEILRAIGKGSFGKVCIVQK---NDTKKMYAMKYMNKQKCVERNEVRNVF 69

  Fly   248 NERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAM 312
            .|.:|:..:.|.|:|.|.|:||....:::::|.|.||||...|.:.|.|.||.||.::.||.:|:
Human    70 KELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMAL 134

  Fly   313 NHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVNRK---G 374
            ::|....||:||:||:|||||||||:.:|||.::......::..:..||..|||||:.:.:   |
Human   135 DYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSRKGAG 199

  Fly   375 HDFAADWWSFGVLMYEMLTGNLPFH---GQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRN 436
            :.||.||||.||..||:|.|..|:|   ..:.:|.::....:.:..|...|.|..|||:.|.:.|
Human   200 YSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPN 264

  Fly   437 PQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSR---DDAFYFDVEYTSKSP 495
            |..|...    :.|::...:...|:|..:.:|::.|.|||...|   |..|..:.......|
Human   265 PDQRFSQ----LSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKP 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	107/303 (35%)
		STKc_RSK_C	567..883	CDD:270993
STK32A	NP_001274669.1	STKc_Yank1	22..281	CDD:270730	99/265 (37%)