Protein Alignment S6kII and sgk-1

DIOPT Version :9

• Sequence 1: NP_001259779.1
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001041299.1
• Gene: sgk-1 / 181697
• WormBaseID: WBGene00004789
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 363
• Identity: 136/363 - (37%)
• Similarity: 205/363 - (56%)
• Gaps: 22/363 - (6%)

  Fly   169 EDTEPLYETENEFELKEVIKEGHDK---ADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAM 230
            ||....:..|:..:.:..:..|..:   |..:.|:.|..:|:||||:|:.||.   |:...:|||
 Worm   102 EDVRRFFHLESPDDDENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRH---KETKKIYAM 163

  Fly   231 KVLKKATLKVKDRVRST-NERKILA-DVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKE 293
            |:|.|..::.|:.|:.. .||.:|. :..|.|:|.||::||...|||.:||.|.||:||:.|.:|
 Worm   164 KILSKEHIRKKNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQRE 228

  Fly   294 VMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYS- 357
            ..|:|...:||.||:|.|:.:||...||||||||||:|||:.|::.||||||.|:.:.||||.|
 Worm   229 KHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTST 293

  Fly   358 FCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLS 422
            ||||.||:||||:.:|.:|...|||..|.::|||:.|..||:.:...|..::|:...|.:..|:|
 Worm   294 FCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNIS 358

  Fly   423 PEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSRDDAFYFD 487
            .....|:..|.:::...||| ......||:.|.||..:||.:|..::::.||||.|..    ..|
 Worm   359 VPCSELITGLLQKDRSKRLG-HRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKN----AMD 418

  Fly   488 VEYTSKSPRDSPGGPISASAHEI--------FRGFSFV 517
            ....||...:....|.|.:..::        |..|:||
 Worm   419 TSNISKEFVEIQIDPSSLAPQQLAVTHRDHDFENFTFV 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_001259779.1	S_TKc	199..457	CDD:214567	112/260 (43%)
		STKc_RSK_N	203..517	CDD:270734	127/324 (39%)
		STKc_RSK_C	567..883	CDD:270993
		S_TKc	568..834	CDD:214567
sgk-1	NP_001041299.1	S_TKc	135..392	CDD:214567	112/260 (43%)
		STKc_SGK	139..456	CDD:270727	127/324 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940