Protein Alignment S6kII and LOC1272910

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_061502626.1
• Gene: LOC1272910 / 1272910
• VectorBaseID: AGAMI1_004234
• Length: 899
• Species: Anopheles gambiae
• Alignment Length: 887
• Identity: 579/887 - (65%)
• Similarity: 656/887 - (73%)
• Gaps: 101/887 - (11%)

  Fly    88 VTSSQRRQQLQQVQQQSALQAALEQHH-----------------ISPT-------ADLDSARKRP 128
            :|...|..||.| :|.:..|....|||                 :.|.       |...:.::.|
Mosquito    51 LTHDHRHAQLHQ-EQPAQHQYLPHQHHHQHQPHPQPHQYSRQHPVPPAGMVTYAPAHTAAGQQEP 114

  Fly   129 T--------------HRTLCPPP-------ELMELSDSESQGGVETGGRREGAT------GRSAP 166
            .              ||...|.|       |.|:| |....||.:....|..||      |.:..
Mosquito   115 LLDGAVVADSGTYRYHRGDSPEPGLVVGAEEAMDL-DVTGGGGGDLSQLRGDATYPNAGAGGNGG 178

  Fly   167 DLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMK 231
            |          |:|.::|::|:|||:||||||||||:||||||||||||||||:|.|||||||||
Mosquito   179 D----------EHEIDIKDIIREGHEKADPSQFELLKVLGEGSFGKVFLVRKIVGIDAGTLYAMK 233

  Fly   232 VLKKATLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMF 296
            |||||||||||||||||||.|||||||||||:|||||||||||||||||||||||||||||||||
Mosquito   234 VLKKATLKVKDRVRSTNERNILADVGHAFIVKLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMF 298

  Fly   297 TEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGT 361
            |||||||||||||||:||||::|||||||||||||||:.||||||||||||||||||||||||||
Mosquito   299 TEEDVKFYLAELALALNHLHSIGIIYRDLKPENILLDQDGHIALTDFGLSKQPLDGSKTYSFCGT 363

  Fly   362 VEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQ 426
            |||||||:||||||.||||||||||||:|||||||||||..|.:||||||::|||||||||||||
Mosquito   364 VEYMAPEVVNRKGHTFAADWWSFGVLMFEMLTGNLPFHGSNRNDTMNQILKTKLGMPENLSPEAQ 428

  Fly   427 SLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSRDDAFYFDVEYT 491
            ||||||||||||||||||..||.|||.|.|||.:||...|||:||||||||||||||||||.|||
Mosquito   429 SLLRALFKRNPQNRLGAGPNGIEDIKRHEFFANVDWDAFERKEVRPPFIPAVSRDDAFYFDSEYT 493

  Fly   492 SKSPRDSPGGPISASAHEIFRGFSFVAPVLLEGQ---CAGSNMCSTSASPLHSIAPIPAAPVGAP 553
            :|||:||||||:|||||||||||||:||.||:.|   ..||||.....         ||:.....
Mosquito   494 NKSPKDSPGGPVSASAHEIFRGFSFIAPGLLDEQPNFANGSNMVMQQQ---------PASRSPFS 549

  Fly   554 RTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEE 618
            ..:|||.|..|..||||::||||||||:||:||||.:|||||||:|:|         :..||.||
Mosquito   550 NEIPGVKPVAFGDEYNLMEELGRGTFSICRMCEHRTTKKHYAVKIIDK---------SYHDCREE 605

  Fly   619 VEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVA 683
            |||:|||||||||||||.|:|||...||||||||||||||||||:..|.|.||||||||:.||||
Mosquito   606 VEILLRYGNHPNIVTLYGVHEDASYVYLVMELLKGGELLDRILAIHFMAEQEASAVLRTVVSAVA 670

  Fly   684 YLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQ 748
            ||||||||||||||||::|||:..|||:|||||||||||||||||||||||||||||||||||:|
Mosquito   671 YLHEHGVVHRDLKPSNLLYASVNHTPESLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKKQ 735

  Fly   749 GYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQ 813
            |||||||||||||||||||.|:||||||||||||:||.|||||::|..:.:|..||...|:||||
Mosquito   736 GYDLACDIWSLGVLLYIMLDGKTPFASTPNDSPDMILARIGSGKVDLETGKWPTISDEVKDLLRQ 800

  Fly   814 MLHIVPENRPTAARILEHDWLREQFAGGVQL------TEYAVAPGSQLSLGAQQQQQNHISM--- 869
            ||||||..|||||:||.|.||..   .|.:|      |::|.   |:..:..:.|......:
Mosquito   801 MLHIVPSRRPTAAQILRHPWLSR---SGPRLMYNTVGTQHAT---SERPMVVEPQDTKPACVNTE 859

  Fly   870 ALRGAVDATFRAIAIPQAANVGPVELSMLAKRRAKDRANLHS 911
            |::|||.||||||:.|||||:|||.:|.||:|| .|:.| ||
Mosquito   860 AIKGAVHATFRAISSPQAANLGPVGMSDLARRR-MDKMN-HS 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	279/313 (89%)
		STKc_RSK_C	567..883	CDD:270993	220/324 (68%)
LOC1272910	XP_061502626.1	None