Protein Alignment S6kII and prkg2

DIOPT Version :10

• Sequence 1: NP_523437.2
• Gene: S6kII / 33139
• FlyBaseID: FBgn0262866
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_021331649.2
• Gene: prkg2 / 100125912
• ZFINID: ZDB-GENE-060531-80
• Length: 769
• Species: Danio rerio
• Alignment Length: 375
• Identity: 125/375 - (33%)
• Similarity: 194/375 - (51%)
• Gaps: 30/375 - (8%)

  Fly   139 LMELSDSESQGGVETGGRREGA-TGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQF--- 199
            |....||.::...:...:|.|: |..:.|...|...|.|.|:.|            |....|
Zfish   408 LQSYVDSLARDDKKRNAKRSGSCTPPNTPVSHDMIELKERESSF------------ASTIPFTCL 460

  Fly   200 ELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATL---KVKDRVRSTNERKILADVGHAFI 261
            |.:..||.|.||:|.||:.   |:....:|:|.:||..:   :.::.:.|  ||:||.:....||
Zfish   461 EAIATLGVGGFGRVELVKL---KNENVTFALKCIKKRHIVDNRQEEHIYS--ERRILLETNCPFI 520

  Fly   262 VRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLK 326
            |:::..::....:|::|:...||::::.|.....|.|...||.:..:..|..:||..||||||||
Zfish   521 VKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEYTAKFCVGCVTEAFEYLHNNGIIYRDLK 585

  Fly   327 PENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEM 391
            |||::||..|::.|.|||.:|:...|.:|::||||.||:||||:..|||..:.|:||.|:|::|:
Zfish   586 PENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHGLSVDFWSLGILIFEL 650

  Fly   392 LTGNLPFHGQTRQETMNQILR--SKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAH 454
            |||:.||.|..:......||:  .|:..|:.::.....|:|.|.::||..|||....||.|||.|
Zfish   651 LTGSPPFTGSDQMIIYTFILKGIEKMDFPKKITKRPGDLIRKLCRQNPSERLGNLKNGITDIKKH 715

  Fly   455 CFFATIDWVRLERKQVRPPFIPAV-SRDDAFYFDVEYTSKS--PRDSPGG 501
            .:|....|..|:.:.:..|....| ...|..||| .|..:.  |.|...|
Zfish   716 RWFTGFSWSGLKARNLISPLKREVKGPTDHSYFD-SYPPEEEIPPDEMSG 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6kII	NP_523437.2	STKc_RSK_N	203..517	CDD:270734	110/307 (36%)
		STKc_RSK_C	567..883	CDD:270993
prkg2	XP_021331649.2	None