DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0196 and AT5G15070

DIOPT Version :9

Sequence 1:	NP_001097041.2	Gene:	l(1)G0196 / 33137	FlyBaseID:	FBgn0027279	Length:	1846	Species:	Drosophila melanogaster
Sequence 2:	NP_001190313.1	Gene:	AT5G15070 / 831359	AraportID:	AT5G15070	Length:	1059	Species:	Arabidopsis thaliana

Alignment Length:	1074	Identity:	446/1074 - (41%)
Similarity:	603/1074 - (56%)	Gaps:	208/1074 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LGLQDGNGDTDFGDSNDGMDSDTSTSSSNSKQVVVGICAMAKKTQSKPMKEILTRL---GEFEFI 96
            :|:::|          .|:|          |::.:|:|.|.||..|.||.:|:.|:   ||||
plant     1 MGVEEG----------AGVD----------KKITIGVCVMEKKVFSAPMGQIMDRIHAFGEFE-- 43

  Fly    97 KLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQDRRRVY 161
             ::.|.:.|||.:||::||.||||::|:|.|:||||...|:.||.||::|.|..||.:.|||:||
plant    44 -IIHFGDKVILEDPVESWPICDCLIAFYSSGYPLEKVQAYSSLRKPFLVNELDPQYLLHDRRKVY 107

  Fly   162 AILEKEGIEIPRYAVLDRDSPDPKHHELIESEDHVEVNGITFNKPFVEKPVSAEDHNIYIYYPTS 226
            ..||..||.:||||.::|..||......:|.||.|||.|..|.||||||||:.:||:|.||||:|
plant   108 EHLEMYGIPVPRYACVNRKVPDEDLDYFVEEEDFVEVKGERFWKPFVEKPVNGDDHSIMIYYPSS 172

  Fly   227 AGGGSQRLFRKIGSRSSVYSPE-SRVRKTGSFIYEDFMPTDGTDVKVYTVGPDYAHAEARKSPAL 290
            ||||.:.||||:|:|||.:.|: .|||:.||:|||:||||.|||||||||||:||||||||||.:
plant   173 AGGGMKELFRKVGNRSSEFHPDVRRVRREGSYIYEEFMPTGGTDVKVYTVGPEYAHAEARKSPVV 237

  Fly   291 DGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSFVKNSN 355
            ||.|.|:.:|||:||||:|..:||.::|:||:||:|.||||||||:.|.||||||||:||||||.
plant   238 DGVVMRNPDGKEVRYPVLLTPAEKQMAREVCIAFRQAVCGFDLLRSEGSSYVCDVNGWSFVKNSY 302

  Fly   356 KYYDDCAKILGNMILRELTPTLH--IPWSVPFQLDDP-----------PIVPTTFGKMMELRCVV 407
            |||||.|.:|..|.|....|.|.  ||..:|:::::|           ..:..|||:..|||||:
plant   303 KYYDDAACVLRKMFLDAKAPHLSSTIPPILPWKINEPVQSNEGLTRQGSGIIGTFGQSEELRCVI 367

  Fly   408 AVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYK-LGHVKLKRPKQLQEILDIARFLLSEI---H 468
            |::||||||||||:|::|...|...:..||:|.| ....|||...|||::||..|.|:...   .
plant   368 AIVRHGDRTPKQKVKLKVTEEKLLNLMLKYNGGKPRAETKLKTAVQLQDLLDATRMLIPRARSGE 432

  Fly   469 TKAHAEIEEKESKLEQLKNVLEMYGHFSGINRKVQMK-----YQPKGRPRGSSSDDTNLAADQPV 528
            :.:.||..|...||.|:|.|||..||||||.||||:|     ..||....|..        ::||
plant   433 SDSDAEDLEHADKLRQVKAVLEEGGHFSGIYRKVQLKPLKWVNVPKSDGEGEE--------ERPV 489

  Fly   529 EPSLVLILKWGGELTPAGRIQAEELGRIFR-CMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIY 592
            |  .:::||:||.||.|||.|||||||.|| .||||          :|.||||||||:|||||||
plant   490 E--ALMVLKYGGVLTHAGRKQAEELGRYFRNNMYPG----------EGTGLLRLHSTYRHDLKIY 542

  Fly   593 ASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDSSKYQNLAKGRLHEL--- 654
            :||||||||:|||||||||.|||:||||||.:|  :..:.:||...::|.....||.:|:|:
plant   543 SSDEGRVQMSAAAFAKGLLDLEGQLTPILVSLV--SKDSSMLDGLDNASSEMEAAKAQLNEIITA 605

  Fly   655 ---MQNDREFSK----EDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDP 712
               |.:|...|:    .|...:.|...:.:.:.:...|...:   .|.||.::....::    :|
plant   606 GSKMVHDHVSSELPWMTDGAGLPPHADEHLPELVKLAKKVTE---QVRLLAQDEHENLA----EP 663

  Fly   713 KTKDAILYH-----------------------GETWDLMRCRWEKIEKD-FSTKSKLFDISKIPD 753
            ...|.:..:                       .|.:.||..||.|:|:| ::.:.:.|||::|||
plant   664 SAYDVVPPYDQAKALGKSNIDVGRIAAGLPCGSEGFLLMFARWRKLERDLYNERRERFDITQIPD 728

  Fly   754 IYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIGQGICSPLLRKIKGD 818
            :||..||||.||.| |.....:||:..|:.|||.|||.|||:.||:||.||..|...||.||..|
plant   729 VYDSCKYDLLHNSH-LDLKGLDELFKVAQLLADGVIPNEYGINPQQKLKIGSKIARRLLGKILID 792

  Fly   819 LQRNIDEV----------------------EDEFMN----------------------------- 832
            |:...:|.                      ||.:..
plant   793 LRNTREEAMSVAELKNSQDQVSVSLYSSRKEDRYSQPKLFVKSDELRRPSTGENKEEDDDKETKY 857

  Fly   833 RLNPHYSHGVASPQRHVRTRLYFTSESHVHSLLTVLRYGGLLNVVTDEQ---WRRAMDYISMVSE 894
            ||:|.|:: |.:|:||||||||||||||:|||:.||||..|...:..|:   .:.|:|.:....|
plant   858 RLDPKYAN-VMTPERHVRTRLYFTSESHIHSLMNVLRYCNLDESLQGEESLVCQSALDRLCKTKE 921

  Fly   895 LNYMSQIVIMLYED-------------PTKDPTSEERFHVELHFSPGVNCCVQKNLPPGPGFRPH 946
            |:|||.:|:.|:|:             ...||   :||.:||.||.|.      :|.|
plant   922 LDYMSYVVLRLFENTETLKHKNYCLQISLDDP---KRFRIELTFSRGA------DLSP------- 970

  Fly   947 SHGDNACNVSLQSSDESNPARIEEENDSNSGEER 980
                      |:..||...:.:.|......|.||
plant   971 ----------LEKKDEEAESLLREHTLPIMGPER 994

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0196	NP_001097041.2	His_Phos_2	402..926	CDD:278743	240/634 (38%)
AT5G15070	NP_001190313.1	ATP-grasp_4	102..293	CDD:302634	120/190 (63%)
AT5G15070	NP_001190313.1	His_Phos_2	362..938	CDD:278743	234/606 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	337	1.000	Domainoid score	I248
eggNOG	1	0.900	-	-		E1_KOG1057
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49409
Inparanoid	1	1.050	718	1.000	Inparanoid score	I121
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D93740at2759
OrthoFinder	1	1.000	-	-		FOG0001610
OrthoInspector	1	1.000	-	-		otm2481
orthoMCL	1	0.900	-	-		OOG6_101402
Panther	1	1.100	-	-	O	PTHR12750
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1173
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830