Protein Alignment l(1)G0196 and ppip5k1a

DIOPT Version :9

• Sequence 1: NP_001097041.2
• Gene: l(1)G0196 / 33137
• FlyBaseID: FBgn0027279
• Length: 1846
• Species: Drosophila melanogaster
• Sequence 2: XP_021333641.1
• Gene: ppip5k1a / 556748
• ZFINID: ZDB-GENE-100426-4
• Length: 1404
• Species: Danio rerio
• Alignment Length: 1531
• Identity: 740/1531 - (48%)
• Similarity: 926/1531 - (60%)
• Gaps: 204/1531 - (13%)

  Fly    18 QQQNPHQSQ---PQQRVGFYLGL--QDGNGDTDFGDSNDGM---DSDTSTSSSNSKQVVVGICAM 74
            :..:|.:||   |:    |::|.  .:..|..|:......|   :.|....|...:|:|:|||.|
Zfish     3 EPSSPGESQRGAPR----FFVGCAEDESEGLDDYASMRTDMELYEDDLEDDSPPERQIVMGICCM 63

  Fly    75 AKKTQSKPMKEILTRLGEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQL 139
            .||::||||.:||.||.:||:|.:|.|.|:|||.|||:.||.||||:|||||||||:||:.||:|
Zfish    64 MKKSKSKPMTQILERLCKFEYITVVIFPEDVILNEPVEKWPLCDCLISFHSKGFPLDKAVSYAKL 128

  Fly   140 RNPFVLNNLHMQYDIQDRRRVYAILEKEGIEIPRYAVLDRDSPDPKHHELIESEDHVEVNGITFN 204
            |||.::|:|:|||.|||||.||.||::|||::||||||:||...|....|||:||.|||||..|.
Zfish   129 RNPLLINDLNMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPDKPDECNLIEAEDQVEVNGEVFL 193

  Fly   205 KPFVEKPVSAEDHNIYIYYPTSAGGGSQRLFRKIGSRSSVYSPESRVRKTGSFIYEDFMPTDGTD 269
            ||||||||||||||:||||||||||||||||||||||||||||||.||||||:|||:||||||||
Zfish   194 KPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTD 258

  Fly   270 VKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLL 334
            ||||||||||||||||||||||||||||||||||||||:|...|||::|||||||||||||||||
Zfish   259 VKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCLAFKQTVCGFDLL 323

  Fly   335 RANGKSYVCDVNGFSFVKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGK 399
            ||||.|||||||||||||||.||||||||||||:::|||.|...||||:|.:.:|.||||||.|.
Zfish   324 RANGHSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFQIPWSIPTEAEDIPIVPTTSGT 388

  Fly   400 MMELRCVVAVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLL 464
            |||||||:|||||||||||||||:|||:..|||:||||.|||.|.:|||:||||||:|||.|.||
Zfish   389 MMELRCVIAVIRHGDRTPKQKMKMEVRNAMFFELFEKYGGYKTGKLKLKKPKQLQEVLDITRTLL 453

  Fly   465 SEIHTKAHAEIEEKESKLEQLKNVLEMYGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVE 529
            ::|......|||||:|||||||.||||||||||||||||:.|.|.|:|:.||.::     |...|
Zfish   454 ADIGQHTDCEIEEKKSKLEQLKTVLEMYGHFSGINRKVQLTYLPHGQPKTSSEEE-----DTRKE 513

  Fly   530 -PSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYA 593
             ||::|:||||||||||||:|||||||.||||||||||  ||:|..|.||||||||:||||||||
Zfish   514 GPSILLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYA 576

  Fly   594 SDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDS-SKYQNLAKGRLHELMQN 657
            ||||||||||||||||||||||||||||||||||||.|||||||.:| |..|...|.||||:||.
Zfish   577 SDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDNDIESLSGCQQRVKARLHEIMQK 641

  Fly   658 DREFSKEDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHG 722
            |:.|::||.:.:.|..|.|:..::..|:|||..|..|:.|::.|...|..:.:|||:.|..|||.
Zfish   642 DKVFTEEDYDRLAPTCSSSLVNSMRAVENPVCICDQVYTLVQSLTSQIRKRLEDPKSADLQLYHS 706

  Fly   723 ETWDLMRCRWEKIEKDFSTKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADI 787
            ||.::|..||.|:|:||..||..:|||||||||||||||:|||. :|..:...||:..::.||||
Zfish   707 ETLEMMLQRWSKLERDFRMKSGRYDISKIPDIYDCIKYDVQHNS-SLGLEDTLELFKLSRALADI 770

  Fly   788 VIPQEYGLTPQEKLAIGQGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPHYSHGVASPQRHVRTR 852
            |||||||:...|||.|....|.||::||:.||||.   .|||.:|:|:|.||.||.||.||||||
Zfish   771 VIPQEYGINTVEKLDIAYAYCLPLVKKIQLDLQRT---HEDESVNKLHPLYSRGVLSPGRHVRTR 832

  Fly   853 LYFTSESHVHSLLTVLRYGGLLNVVTDEQWRRAMDYISMVSELNYMSQIVIMLYEDPTKDPTSEE 917
            |||||||||||||::.||||||:...||||:|||||:|.|||||||:|||||||||..|||:|||
Zfish   833 LYFTSESHVHSLLSIFRYGGLLDEENDEQWKRAMDYLSAVSELNYMTQIVIMLYEDNNKDPSSEE 897

  Fly   918 RFHVELHFSPGVNCCVQKNLPPGPGFRPHSHGDNACNVSLQSSDESNPARIEEENDSNSGEEREG 982
            ||||||||||||....:::.|.|.||||.|                      .|||
Zfish   898 RFHVELHFSPGVKVSEEESAPMGFGFRPAS----------------------AEND--------- 931

  Fly   983 KKRGTSGQRSTDRSAERISPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMDLAKRLN----E 1043
                   |:.||..:           ||..|:....:.:|:.  ..:|......|.:...    |
Zfish   932 -------QKQTDPGS-----------LENLSRDEPDRALPLS--EAISTQRKSPLIRNRKTGSME 976

  Fly  1044 ELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCA--------KEPVSSPDFGDNS 1100
            .|:.....:....|        :.|.|..:|...:|......||        ....|:|:..|.:
Zfish   977 VLSESSSSKGGSYR--------LFPSCSRQSPEMKQSGLGSQCAGLFSTTVLGGSSSAPNLQDYA 1033

  Fly  1101 RTRSSEFGETCHARVGTASNSDG----------------GGSHPRADHRTAFQIRVTNSLSFFKI 1149
            ||...:|..      |:.:..||                ..|.|..:|:.|..:|      .|..
Zfish  1034 RTHRKKFSS------GSLTYKDGTQDDTSTRVIKQPLWWSFSEPLEEHQVAQLLR------RFSN 1086

  Fly  1150 DSSTNELPLSDIDFSLHPPTPQCGPLSHKRFHILTMRR-MESCDDGAE----LEQVRHLPQISPM 1209
            |.:.......|..|:.|  ..||.      :|:...|. :.|..|..|    .|....:|.|.|:
Zfish  1087 DPNIGHPFCLDSAFAHH--LHQCS------YHLRLFRNWLISGQDPLEYIYGFEGCSMVPSIYPL 1143

  Fly  1210 AT--NERPLSSCN------CSSSAAQAHSHSKSLMDLAQAVVMTSPQETG----PNSEQGCDPTT 1262
            .|  |...|...|      |.::   ..||:::...|: |:..:..|.||    |:.      ..
Zfish  1144 ETLHNSLSLKQVNEFLTTVCENA---GDSHTRTTRALS-AMFDSQNQPTGESYIPHR------VL 1198

  Fly  1263 AADVSVSSFDDDFQLSSSAPAILMSAHFGNRPVVASLSSMVHVTTSPSASTLQLCRDKDKALASG 1327
            ::.||:....|.....||.|:..:|:        |..||.....|||..|    ..:|.......
Zfish  1199 SSSVSLRQRSDRPPWYSSGPSSTVSS--------AGPSSPTTADTSPRFS----FSEKITLTPQS 1251

  Fly  1328 TSSAHSKATSNSCGQLSMAGSAPVVTE-------NPFRFTVSSLGSAATNTA--CFVGSFEPIEE 1383
            :...|....:|:|..:|:.....:.:|       :|.....|.:.|..|::|  |...|  |..:
Zfish  1252 SEEIHQIPQNNNCHTVSLTSEPSIPSEDPHSSIPSPIMERPSQITSDGTDSAGQCLTES--PSCD 1314

  Fly  1384 QITSIVEVDSKPLQPEPQVVYNLP---TVLITGTASSSELSTKLNSNILPTVTNAFSAIDTEIND 1445
            :.:|....:..|..|.|:....||   .||:....||||..:...:.:.|...:.|  .||:  :
Zfish  1315 EGSSPNTAEPSPPSPLPESFRGLPGSLPVLLELRESSSETGSSAQTPLSPEEPDEF--FDTQ--E 1375

  Fly  1446 EIGISKEVGIGTIRITNTHTPCNKATVTRPDTKIAI 1481
            .:...:|               |.|::..|.|.:.:
Zfish  1376 TVDAWRE---------------NPASLPHPGTPLEV 1396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0196	NP_001097041.2	His_Phos_2	402..926	CDD:278743	346/525 (66%)
ppip5k1a	XP_021333641.1	His_Phos_2	391..906	CDD:306768	346/525 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589159
Domainoid	1	1.000	687	1.000	Domainoid score	I131
eggNOG	1	0.900	-	-		E1_KOG1057
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1303	1.000	Inparanoid score	I153
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D37386at33208
OrthoFinder	1	1.000	-	-		FOG0001610
OrthoInspector	1	1.000	-	-		otm24603
orthoMCL	1	0.900	-	-		OOG6_101402
Panther	1	1.100	-	-	LDO	PTHR12750
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1640
SonicParanoid	1	1.000	-	-		X1173
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790