Protein Alignment l(1)G0196 and ppip5k1

DIOPT Version :10

• Sequence 1: NP_001097041.2
• Gene: l(1)G0196 / 33137
• FlyBaseID: FBgn0027279
• Length: 1846
• Species: Drosophila melanogaster
• Sequence 2: XP_002932309.2
• Gene: ppip5k1 / 100493265
• XenbaseID: XB-GENE-6258750
• Length: 1361
• Species: Xenopus tropicalis
• Alignment Length: 1455
• Identity: 726/1455 - (49%)
• Similarity: 913/1455 - (62%)
• Gaps: 207/1455 - (14%)

  Fly    33 FYLGLQDGNGDTDFGDSN------DGMDSDTSTSSS-NSKQVVVGICAMAKKTQSKPMKEILTRL 90
            |::|.:|  .:|||.:||      |..:.|....:: ..:|:|||||||.||::||||.:||.||
 Frog    17 FFVGARD--DETDFLESNMNQEEVDFYEEDEDEEATPPERQIVVGICAMTKKSKSKPMTQILERL 79

  Fly    91 GEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQ 155
            .:||:|.:|...|:|||.|||:|||.||||:|||||||||:||:.|::|||||::|:|:|||.||
 Frog    80 CKFEYITVVIMSEDVILNEPVENWPICDCLISFHSKGFPLDKAVAYSKLRNPFLINDLNMQYFIQ 144

  Fly   156 DRRRVYAILEKEGIEIPRYAVLDRDSPDPKHHELIESEDHVEVNGITFNKPFVEKPVSAEDHNIY 220
            |||.||.||::|||::||||||:||...|:...|:|.||||||||..|.||||||||||||||:|
 Frog   145 DRREVYRILQQEGIDLPRYAVLNRDPDWPEECNLVEGEDHVEVNGEVFPKPFVEKPVSAEDHNVY 209

  Fly   221 IYYPTSAGGGSQRLFRKIGSRSSVYSPESRVRKTGSFIYEDFMPTDGTDVKVYTVGPDYAHAEAR 285
            ||||||||||||||||||||||||||.||.||||||:|||:||||||||||||||||||||||||
 Frog   210 IYYPTSAGGGSQRLFRKIGSRSSVYSSESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEAR 274

  Fly   286 KSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSF 350
            ||||||||||||||||||||||:|...|||::|||||||||||||||||||||.|:|||||||||
 Frog   275 KSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCLAFKQTVCGFDLLRANGHSFVCDVNGFSF 339

  Fly   351 VKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGKMMELRCVVAVIRHGDR 415
            ||||.||||||||||||:|:|||.|..|||||:|.:.:|.||||||.|.|||||||:||||||||
 Frog   340 VKNSMKYYDDCAKILGNIIMRELAPQFHIPWSIPTEAEDIPIVPTTSGTMMELRCVIAVIRHGDR 404

  Fly   416 TPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLLSEIHTKAHAEIEEKES 480
            |||||||:||||.:|||:||:|||||.|.:|||:|:||||:|||||.||:|:.|....||||::|
 Frog   405 TPKQKMKMEVRHSRFFELFERYDGYKTGKLKLKKPEQLQEVLDIARLLLAELGTHNDCEIEERKS 469

  Fly   481 KLEQLKNVLEMYGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVEPSLVLILKWGGELTPA 545
            ||||||.||||||||||||||||:.|.|.|:|:.||.:| :...|   .|||:|:||||||||||
 Frog   470 KLEQLKTVLEMYGHFSGINRKVQLTYLPHGQPKTSSEED-DARKD---SPSLLLVLKWGGELTPA 530

  Fly   546 GRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGL 610
            ||:|||||||.||||||||||  ||:|..|.||||||||:|||||||||||||||||||||||||
 Frog   531 GRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGL 593

  Fly   611 LALEGELTPILVQMVKSANTNGLLDNDCDS-SKYQNLAKGRLHELMQNDREFSKEDRELINPCNS 674
            |||||||||||||||||||.|||||:|.|| |..|...|.||||:||.|:|||:|::|.:.|.:|
 Frog   594 LALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQQKVKARLHEIMQKDKEFSEEEQEKLAPTSS 658

  Fly   675 KSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHGETWDLMRCRWEKIEKDF 739
            .||..:::.::|||..|..|:.||..|...|..:.:|||:.|..|||.||.:||..||.|:|:||
 Frog   659 TSIVNSMECIQNPVKTCDSVYSLIENLTSQIQKRLEDPKSADLQLYHSETLELMLQRWSKLERDF 723

  Fly   740 STKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIG 804
            ..|:..:|||||||||||:|||:|||. :|:.:..:||:..:|:||||:||||||:..:|||.|.
 Frog   724 RMKNGRYDISKIPDIYDCVKYDVQHNS-SLKLEGTDELFKISKSLADIIIPQEYGINKEEKLEIA 787

  Fly   805 QGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPHYSHGVASPQRHVRTRLYFTSESHVHSLLTVLR 869
            .|.|.||::||:.||||.   .|||.:|:|:|.||.||.||.|||||||||||||||||||::.|
 Frog   788 VGYCLPLIKKIQLDLQRT---HEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSIFR 849

  Fly   870 YGGLLNVVTDEQWRRAMDYISMVSELNYMSQIVIMLYEDPTKDPTSEERFHVELHFSPGVNCCVQ 934
            |||||:...|:||:|||||:|.|||||||:|||||||||..||.:|||||||||||||||..|.:
 Frog   850 YGGLLDESKDQQWKRAMDYLSAVSELNYMTQIVIMLYEDNNKDASSEERFHVELHFSPGVKGCEE 914

  Fly   935 -KNLPPGPGFRPHS---------HG-----------DNACNVSLQSSDESNP------ARIEEEN 972
             :|.|.|.||||.|         .|           |......|.|:..|.|      :.:....
 Frog   915 DENAPLGFGFRPASAENEDKKTDQGSLEDLTKVKGRDEVDRSILMSALPSEPLSLLRKSPLTRSR 979

  Fly   973 DSNSGEEREGKKRGTSGQRSTDRSAERI-SPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMD 1036
            .:.|.|....|..|..|:|.. ||.|.: ||.    .:.|:||...:
 Frog   980 KTGSMEVMNAKSTGNRGRRRR-RSGEPLHSPC----SITLQSKAMST------------------ 1021

  Fly  1037 LAKRLNEELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCAKEPVSSPDFGDNSR 1101
                  ..|||.||..::                           ||.......:.:.....:|.
 Frog  1022 ------TNLASWQQVLSE---------------------------TSSKAGGYRLFTSFARQSSD 1053

  Fly  1102 TRSSEFGETCHARVGTASNSDGGGSHPR---ADHRTAFQIRVTNSLSFFKIDS--STNELPLSDI 1161
            .:.|..|..|   .|..|.:..|||...   .|:..:.:.:::::.|....|.  |...:....:
 Frog  1054 MKQSGLGSQC---TGLFSTTVLGGSSSAPNLQDYARSHRKKISSAASLTYKDELLSMPAVKRFSV 1115

  Fly  1162 DFSLHPP--------TPQCGPLS--HKRFHILTMRRMES-----CDDGAELEQVRHLPQISPMAT 1211
            .|:.||.        .|...||.  |   :.|::|::.|     |...|:....|
 Frog  1116 SFAKHPTNGFEGCSMVPTIYPLETLH---NSLSLRQVNSFLTAVCKQFADTHSRR---------- 1167

  Fly  1212 NERPLSSCNCSSSAAQAHSHSKSLMDLAQAVVMTSP------------QETGPN---SEQGCDPT 1261
                 ||..|.|..:   ||:.....|...::.:|.            ..:||:   |..|....
 Frog  1168 -----SSAGCDSMIS---SHTSGDTYLPHRILSSSSLHYRHRSERPPWYSSGPSSTVSSAGPSSP 1224

  Fly  1262 TAADVSVS-----------------SFDDDFQLSSS---APAILMSAHFGNRPVVASLSSMVHVT 1306
            ||.|:|..                 :.:::.|:..|   ..|.....|....|:.:..:.:....
 Frog  1225 TALDLSARFNFSDKTSLTEEQRKKLNLEENLQVQKSTGEGQASNQEIHQLEEPLHSDCTYLPPEP 1289

  Fly  1307 TSPSASTLQLCRDKDKALASGTSSAHSKATSNSCGQLSMAGSAPVVTENPFRFTVSSLGSAATNT 1371
            :|.:|:.:|.|.:.:..|.           ..|.|:.|:.|.|           :|.|.:.:|.|
 Frog  1290 SSDAAAPVQRCVEHELQLG-----------IESLGEASVPGQA-----------LSELSAQSTKT 1332

  Fly  1372 ACFVGSFE--PIEEQITSIVEVDSK 1394
            ...:...|  |::||:.:.|.:..:
 Frog  1333 HNQMLHLEQSPVDEQMITEVALQGR 1357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0196	NP_001097041.2	PPIP5K2_N	67..156	CDD:465643	58/88 (66%)
		LysX	<135..373	CDD:439959	194/237 (82%)
		His_Phos_2	402..926	CDD:395259	349/524 (67%)
ppip5k1	XP_002932309.2	PPIP5K2_N	56..145	CDD:465643	58/88 (66%)
		LysX	<145..338	CDD:439959	160/192 (83%)
		His_Phos_2	391..906	CDD:395259	349/524 (67%)