DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cp110 and Ccp110

DIOPT Version :9

Sequence 1:	NP_001033857.1	Gene:	Cp110 / 33136	FlyBaseID:	FBgn0031191	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001101971.1	Gene:	Ccp110 / 361634	RGDID:	1310509	Length:	1007	Species:	Rattus norvegicus

Alignment Length:	637	Identity:	141/637 - (22%)
Similarity:	225/637 - (35%)	Gaps:	216/637 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 PTPQPFVKSIENTSPRRHNRITD--RILQFEQSGLGKLLPKVPDKCILRTSPAVAEDQQDQ--DT 202
            |:|:|   |:..|..|||:|.:.  :||........:|.||..::.:.|.:||.||..:.:  ..
  Rat   365 PSPEP---SMSPTMHRRHSRSSSACQILINNPVNACELSPKGKEEAVDRIAPAAAETNESEIVPK 426

  Fly   203 KDTTARELGSPLAEPANFQRS--RSFTLEEPSQ------------VLVEHMEREALAVKPSQSLA 253
            ..|....:||...........  |...:.:|||            |.||....|...:...:.:.
  Rat   427 PPTDLTGVGSSKVSATKVMSDTIREMVMGKPSQVHQALGNQLGNNVTVEQFAMEGPFIPDGRGMQ 491

  Fly   254 NFE---------------KQTIESQA--KRVNRSARSISSKISHN-------SYN---------- 284
            ..:               .|.:.||.  ......|.|:.:|.|.|       ||:
  Rat   492 KVDGTCIAVPKLHELQPTSQCVSSQTLEDACGLKAASVLAKNSCNVQMELNKSYDVKRPSPLLMQ 556

  Fly   285 ---------------------SNSSAATKSTI-----------ATKTTTAGSSCSRRDREVERII 317
                                 .||....|..:           .....||||:...|:|..||..
  Rat   557 TQNSRQQMDTPPVPRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPHILTAGSAEQERERPPERRY 621

  Fly   318 ERAL---DEHGALEASRKAG-------------VRNYL-RGHRERMNQLVIHQEKERRRMQAEFD 365
            .:..   :::..||.|.|.|             :|..| ..|.::::.|:..||:|:.::|.|.:
  Rat   622 PKGSVYGNKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHVQQLSLLIAEQEREQEQLQKEIE 686

  Fly   366 HQQRQLIEELCAEIDVS---SATE-------NPDSLISQSTSTGDLQRFSPSPTLPSFSEDIEDF 420
            .|:: :::|.....|||   ||.|       :|..|.:..:....||..:.|..|
  Rat   687 EQEK-MLKEKAVTTDVSGLNSALELEWRKRSDPAFLETMLSQVDSLQTSNNSGFL---------- 740

  Fly   421 PTMEDKCQIAGPSSARKRLFSPKPSKDSEPQLLSAPSTPRSLPLRNSSLTNSRRSVQVVRRRSQS 485
                        |||.:..|.            ||...|  |.||
  Rat   741 ------------SSALQYSFG------------SASEVP--LYLR-------------------- 759

  Fly   486 VGGSLVKTITAADREVKKSPAKPGGGAGRPKSSPGKNSSIIAKRGSAPPKSASPTKRLGNKYVEL 550
              |||...:|      |.|..:|.|.| :||.|...:..|.||
  Rat   760 --GSLTSGVT------KLSVTRPFGRA-QPKWSQVFSPEIQAK---------------------- 793

  Fly   551 KQEERQWAATRINAGVRGFLVRRLFATEQVQRIVQTIRDTLIFVLNLHLET-CGHGLDAEEPANL 614
                    ..:|.|..:|||.|:|..|::::::.||::||:.|:.:...|. ...|:.:.:.|:
  Rat   794 --------FNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDAS- 849

  Fly   615 RLKARLLQQLCSASRTLHLIFFQTNIKDRMEIIARDRQRIKTKLLLKHRRLD 666
             |:.|:|.||.:|...:|.|||..:..:||.|:..||:..|.|||   |::|
  Rat   850 -LQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLL---RQMD 897

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Cp110	NP_001033857.1	CALM_bind	53..141	CDD:292644
Ccp110	NP_001101971.1	CALM_bind	31..106	CDD:406433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CNAT
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008395
OrthoInspector	1	1.000	-	-		oto96054
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13594
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890