DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14618 and Trmt10c

DIOPT Version :9

Sequence 1:	NP_608464.1	Gene:	CG14618 / 33134	FlyBaseID:	FBgn0031189	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_083368.1	Gene:	Trmt10c / 52575	MGIID:	1196261	Length:	414	Species:	Mus musculus

Alignment Length:	285	Identity:	70/285 - (24%)
Similarity:	121/285 - (42%)	Gaps:	34/285 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TEKALKEVTPAMLSLNNCPGTTPGTPMSKNQLKKQRKLAEFAELRKLRREREREKKKQKRREAKE 68
            ||:.||       :|..|        .||:..||..:.....|..|..::.::|.|.:.|.|||.
Mouse   108 TEEDLK-------TLMEC--------ASKSAKKKYLRYLYGKEKAKKAKQVKKEMKAEAREEAKR 157

  Fly    69 LGLPVRTGPSRKE------LKKRQ--LADGGKS------GLSVAIDLDYDDLMQERDIVKCVKQC 119
            ..|...|...:::      |..||  :|.|.|.      |..:..|:.||:.|:..::...|.|.
Mouse   158 ARLLETTAEEQQQDFMFLRLWDRQINIALGWKGVQAMQFGQPLVFDMAYDNYMKPSELQNTVSQL 222

  Fly   120 LRIYTINRRSPQPGNLHFTGIRRNGHIHESFKK--NEGWENWHVQYYFDRGHTDIFEHSQLVYLT 182
            |.....|||:..|.:::|..::.:...|....|  .|.|:.. :....::...|:|....::|||
Mouse   223 LESEGWNRRNVDPFHIYFCNLKIDSAYHRELVKRYREKWDKL-LLTATEKSPVDLFPKDSIIYLT 286

  Fly   183 CESDRVLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKT-RAVLSTYHV 246
            .:|..|:...:....|:||..||.|...|...::|....:.|..|||.:::..:. ...|:...:
Mouse   287 ADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRLNIATECLPLDKYLQWEIGNKNLTLDQM 351

  Fly   247 FELLTKVAAGQDWTTAILETIPMRK 271
            ..:|..:....:|..| |:.:|.||
Mouse   352 IRILLCLKNTGNWEEA-LKFVPRRK 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14618	NP_608464.1	tRNA_m1G_MT	105..271	CDD:280003	38/168 (23%)
Trmt10c	NP_083368.1	tRNA_m1G_MT	208..375	CDD:280003	38/168 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1545
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840