DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14618 and Trmt10a

DIOPT Version :9

Sequence 1:	NP_608464.1	Gene:	CG14618 / 33134	FlyBaseID:	FBgn0031189	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_017446278.1	Gene:	Trmt10a / 295496	RGDID:	1594565	Length:	340	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	119/347 - (34%)
Similarity:	172/347 - (49%)	Gaps:	61/347 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTTEKALKEVTPAMLSLNNCPGTTPGTPMSKNQLKKQRKLAEF-----AELRKLRRER----ER 56
            |:||..: .||.||.:...|..| .||...|:.:.:|||..||.     .:|:||.::|    :|
  Rat     1 METTNMS-SEVLPASIEPPNVEG-KPGASDSEEERQKQRVDAEAQPISKRQLKKLMKQRLWEEQR 63

  Fly    57 EKKKQKRREAKELGLPVRTGPSRKELKKR-QL---ADG----------GKSGLSVAIDLDYDDLM 107
            |::|:||:|.::          ||:|::| ||   :||          ..|.|.:.||..:||||
  Rat    64 EQRKEKRKEKRK----------RKKLERRCQLESNSDGNDRKRIRRHVAPSNLRLIIDCSFDDLM 118

  Fly   108 QERDIVKCVKQCLRIYTINRRSPQPGNLHFTGIRRNGHIHESFKKN-EGWENWHVQYYFDRGHTD 171
            ..:||.|..||..|.|..|||:..|...:.|.  ..|.:.::..:| :||.||...:.....:::
  Rat   119 VLKDIKKLHKQIQRCYAENRRASHPVQFYLTS--HGGQLKKNMDENDQGWVNWKDIHIKSEHYSE 181

  Fly   172 IFEHSQLVYLTCESDRVLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMK 236
            :.:...|||||.:|..||..|.....|||||||||||.|||...:|:|.|:..|:|||:|.|.|.
  Rat   182 LIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHNHHKGLTFKQASSYGIKHAQLPLAEFVKMN 246

  Fly   237 TRAVLSTYHVFELLTKVAAGQDWTTAILETIPMRKGAKAKITDKKEPNHCLEQQDEKQKQEAESD 301
            :|.||:..||||::.:.....||..|....:|.||||        .|.|       |..:.:..|
  Rat   247 SRKVLAVNHVFEIILEFLETGDWQEAFFTILPPRKGA--------VPAH-------KACESSPQD 296

  Fly   302 KPTL-----TAVESEIESHSLD 318
            ...|     :|:|.|   |..|
  Rat   297 HQALPGGWDSAIEGE---HGRD 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14618	NP_608464.1	tRNA_m1G_MT	105..271	CDD:280003	65/166 (39%)
Trmt10a	XP_017446278.1	Trm10euk_A	106..281	CDD:349974	69/176 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341704
Domainoid	1	1.000	121	1.000	Domainoid score	I5542
eggNOG	1	0.900	-	-		E1_KOG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6886
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4143
OMA	1	1.010	-	-		QHG53860
OrthoDB	1	1.010	-	-		D1396299at2759
OrthoFinder	1	1.000	-	-		FOG0004809
OrthoInspector	1	1.000	-	-		oto98480
orthoMCL	1	0.900	-	-		OOG6_102182
Panther	1	1.100	-	-	LDO	PTHR13563
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3391
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810