Protein Alignment Usp2 and UBP12

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_012338.1
• Gene: UBP12 / 853242
• SGDID: S000003733
• Length: 1254
• Species: Saccharomyces cerevisiae
• Alignment Length: 1317
• Identity: 217/1317 - (16%)
• Similarity: 325/1317 - (24%)
• Gaps: 723/1317 - (54%)

  Fly   133 NQQPTTTNSTT---------INNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNN 188
            |:.|..|:.||         :|....::.....|..|....:..|.:.|::.|
Yeast    16 NEDPDFTDGTTPCDRLGVDLMNVLDDKDEIKQESVPVSDREIEDTESDASAVS------------ 68

  Fly   189 NQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQ--------------QQQHDDISFIDS- 238
            :..:|...:...|..:..|...|..:    |.|.:::|              |::.|.:..:..
Yeast    69 SFASANELIAEPHAASETNLGTNGQD----GRNVLEQQRDVVARLIEENKETQKEGDKVCIVPKV 129

  Fly   239 -----DDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPR 298
                 .||..|...:.|            ||...:..|..:|.|.:.               |.|
Yeast   130 WYDKFFDPDVTDPEDIG------------PINTRMICRDFENFVLED---------------YNR 167

  Fly   299 PKSTIIASAHSNFAASFEKFSGGLY--------RQTNGETNIE------------SKTSSNARRY 343
            .....||....||.:.....:.|.|        .||.||...|            .|.....||:
Yeast   168 CPYLSIAEPVFNFLSEIYGMTSGSYPVVTNLVINQTTGELETEYNKWFFRLHYLTEKQDGRKRRH 232

  Fly   344 GID------SLS----IKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHG 398
            |.|      |:|    ::..:||..||..:|                              ::|
Yeast   233 GQDDSIMYLSMSALNLVRDLVEKSMNLFFEK------------------------------ADH- 266

  Fly   399 SQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGE 463
                             ||                      :|:|...:...||        |.:
Yeast   267 -----------------LD----------------------VNAVDFKIWFVSE--------GSD 284

  Fly   464 TATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVT 528
            .||                                                      .|:|||..
Yeast   285 IAT------------------------------------------------------DSNVSTFL 295

  Fly   529 VTAAAPNSASDSVSRSLARSPISSTLARSGTGSSSTARSVLPPMTPTSSRYWDR-DSGTSRSSIG 592
                  ||:.:.........||...|              :|.|      :.:| |..||
Yeast   296 ------NSSYEITPLQFLELPIKKLL--------------IPDM------FENRLDKITS----- 329

  Fly   593 TSSALNSSSL---------KHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQE 648
                 |.|.|         .|:....|  .:.::.|.:.|..||.|:||||:|||.:|||.|..:
Yeast   330 -----NPSDLVIEIKPIEGNHHWPSNY--FAYNKLEPASGTTGLVNLGNTCYMNSALQCLVHIPQ 387

  Fly   649 LTRFL--------------RSHHGSRSLSTKDQQILHEFAKLIQEMWTANVHTV------TPMEL 693
            |..:.              ..:||         .:...|:.|:|:::...:..:      .|...
Yeast   388 LRDYFLYDGYEDEINEENPLGYHG---------YVARAFSDLVQKLFQNRMSIMQRNAAFPPSMF 443

  Fly   694 KRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGE-----TLNIDDNLSD----NKKAD 749
            |......:.|:|.|.|||:||||.|.|||||..||..:|.|     :|:..|:::|    .|.||
Yeast   444 KSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPGDDVNDWNVVKKLAD 508

  Fly   750 LTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLP---------------- 798
            .|||.:.:...|::.|||||..||||.|..|.|.|:||||:.|:::|||
Yeast   509 DTWEMHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLPVDTVWDKTIKIFPMNS 573

  Fly   799 ----------------------------------------------------------------- 798
                                                                             
Yeast   574 PPLLLEVELSKSSTYMDLKNYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTLQELIKP 638

  Fly   799 ----------------------------------------------------------------- 798
                                                                             
Yeast   639 ADDVIFYELPVTNDNEVIVPVLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGAIRMKLQNRFVH 703

  Fly   799 ----------------------------------------------------------------- 798
                                                                             
Yeast   704 LSGGYIPFPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTSIKVTDKDKSFFSIKILSVEK 768

  Fly   799 -----SSSR-------------------------------------------------------- 802
                 |::|
Yeast   769 EQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDIYNYSSLVDCAEGVLMQVDDEGDTEG 833

  Fly   803 ----------------------------------------------------------------- 802
                                                                             
Yeast   834 SEAKNFSKPFQSGDDEENKETVTNNENVNNTNDRDEDMELTDDVEEDASTEPELTDKPEALDKIK 898

  Fly   803 ------------------CK--------------------------------------------- 804
                              |:
Yeast   899 DSLTSTPFAILSMNDIIVCEWSELGSNEAFSDDKIYNWENPATLPNKELENAKLERSNAKERTIT 963

  Fly   805 LEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETR--WSKLSNIV 867
            |:.||.||.:.|:|...:...|..||..|:.||...:...|..|:||||||...|  ..|:...|
Yeast   964 LDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATV 1028

  Fly   868 EFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDAL 932
            .||.:|.:|:......:....:.|.|||:.||.|...||||.|..|:....||:.|:|:.|::..
Yeast  1029 NFPITDLDLSRYVVYKDDPRGLIYDLYAVDNHYGGLGGGHYTAYVKNFADNKWYYFDDSRVTETA 1093

  Fly   933 SENHLVSSSAYILFYER 949
            .||. ::.|||:|||.|
Yeast  1094 PENS-IAGSAYLLFYIR 1109

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	128/753 (17%)
		Peptidase_C19R	626..948	CDD:239139	129/752 (17%)
UBP12	NP_012338.1	UBP12	99..1111	CDD:227847	200/1218 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940