Protein Alignment Usp2 and usp11

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_002663119.3
• Gene: usp11 / 568334
• ZFINID: ZDB-GENE-081104-421
• Length: 990
• Species: Danio rerio
• Alignment Length: 816
• Identity: 160/816 - (19%)
• Similarity: 222/816 - (27%)
• Gaps: 422/816 - (51%)

  Fly   550 ISSTLARSGTGSSSTA----------RSVLPPMTPTSSRYWDRDSGTSRSSIGT------SSALN 598
            :||.|..:.|...|.|          |..........||.|.|...||...:..      .|.|:
Zfish   138 LSSNLESTVTAQFSRADKIHAIHQKIRQHFDVSETAESRLWMRSVDTSSERLRNLNMTVLDSCLS 202

  Fly   599 SSSLK----HNSDDGYKTA-----SSSRDEKS----EGLCGLRNIGNTCFMNSVIQCLSHTQELT 650
            |....    .|:|..:.|:     .:|.||.|    .|:|||.|:||||||||.:||||:|..||
Zfish   203 SGMTVIMEIRNADGTWPTSRPQIMRNSADEDSYRGPPGVCGLTNLGNTCFMNSALQCLSNTPPLT 267

  Fly   651 R------FLRSHHGSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAFSTK--H--RMYS 705
            .      :|...:.|..|..|. :|...:|.:|::||:...::|.|    |.|.||  |  ..:.
Zfish   268 EYFLKNLYLEELNFSNPLGMKG-EIAEAYADVIKQMWSGRHYSVVP----RVFKTKVGHFASQFL 327

  Fly   706 DYNQQDAQEFLRFFLDSLHSALNSGVKGETLNI--DDNLSDNKKADLTWEWYTRHENSLVRDLFV 768
            .|.|.|:||.|.|.||.||..||...|.|.:.:  .|...|.:.|:..|..:.|..:|::.|.|.
Zfish   328 GYQQHDSQELLSFLLDGLHEDLNRVKKKEYIELRDADGRPDQEVAEEAWRNHLRRNDSVIVDTFH 392

  Fly   769 GQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSS--------------------------------- 800
            |..||||.|..|...|||||||..||||||.|
Zfish   393 GLFKSTLVCPECNKVSVTFDPFCYLSVPLPVSKERVMEVFYVSLDPTAKPTQYRLIVPKAGRVLD 457

  Fly   801 ----------------------------------------------------------------- 800
                                                                             
Zfish   458 LCTALSQATGVPPNQMTVTDVFNHRFYRIYQSDESLSCILDRDDIFVYQLSSGCVDEDSDEVVLS 522

  Fly   801 ----------------------------------------------------------------- 800
                                                                             
Zfish   523 IYMRERSHYRDYGSGSNSYGTSLFGHPLRMSVPRAHCTPEHLYQLLLERLARYVRPLDPSEEVEE 587

  Fly   801 ----------------------------------------------------------------- 800
                                                                             
Zfish   588 EEEDDEEELYKAQTNGVSDDEGEEDSEEAGSSKKEEEPRASNEVNEQNNGQSEASPSSEGEERAE 652

  Fly   801 ------------------SRC-------------------------------------------- 803
                              |.|
Zfish   653 EEESSSEQERGSSTEEGQSACGSTDTTDGDQSAGAEPSGKEEDEDEEEEDGEEAASCTPANKRHP 717

  Fly   804 ----------------------------------------------------------------- 803
                                                                             
Zfish   718 GRRRYTERRKKALFTIQAVNSNGTTERGMAEAGGSISFSSQPYIAIDWDPDMKKKYYNENEAEKY 782

  Fly   804 ---------------KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLK 853
                           :|:.|::||...|.|:.:....|..||..:..||...:...|:.|:||||
Zfish   783 IKHQSMDVPHQQTTVQLQECIELFTTVETLEEENPWYCPTCKRHQLATKKLDLWSLPEVLIIHLK 847

  Fly   854 RFSETRWS--KLSNIVEFPTSDSELNMGSYGANSNSN---VHYSLYAISNHMGSTAGGHYVALCK 913
            |||.|::|  ||..|||||..|.:.:........||.   ..|.|.::|||.|....|||.:..:
Zfish   848 RFSYTKYSREKLDTIVEFPLRDLDFSGFLLKKTVNSTEPPCPYDLISVSNHYGGLRDGHYTSYAR 912

  Fly   914 HPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYER 949
            :..:.:|:.|:|:.|:.| .|..:|:|:||:|||:|
Zfish   913 NKDNGQWYYFDDSKVTYA-REEQIVTSAAYLLFYQR 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	133/709 (19%)
		Peptidase_C19R	626..948	CDD:239139	133/708 (19%)
usp11	XP_002663119.3	UBP12	15..947	CDD:227847	159/814 (20%)
		DUSP	34..119	CDD:283896
		Ubiquitin_3	133..219	CDD:291502	18/80 (23%)
		Peptidase_C19	242..>419	CDD:271592	73/181 (40%)
		USP7_C2	413..>504	CDD:291217	9/90 (10%)
		Peptidase_C19R	<793..946	CDD:239139	53/153 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940