DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp2 and usp21

DIOPT Version :9

Sequence 1:	NP_001285528.1	Gene:	Usp2 / 33132	FlyBaseID:	FBgn0031187	Length:	950	Species:	Drosophila melanogaster
Sequence 2:	XP_005162186.1	Gene:	usp21 / 563546	ZFINID:	ZDB-GENE-100210-3	Length:	405	Species:	Danio rerio

Alignment Length:	369	Identity:	143/369 - (38%)
Similarity:	206/369 - (55%)	Gaps:	25/369 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 SSSLKHNSDDGYKTASSSRDE--KSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRF--LRSHHGS 659
            |.|:.:.|..|....:....|  ...|..||||:|||||:|:::||||||:.|..:  :|::...
Zfish    34 SQSVLYTSIMGLLLVTDKERELQLGNGQVGLRNVGNTCFLNAIVQCLSHTRSLRDYCLMRAYVQD 98

  Fly   660 RSLSTKDQQILHEFAKLIQEMW--TANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDS 722
            :. |.::..::.||:|::..:|  .|...||.|.:..|.|......:|.|:||||||||||.||.
Zfish    99 KH-SNQEPVLMDEFSKVLAGLWECDAGETTVNPGKFYRVFKESVPYFSGYSQQDAQEFLRFLLDR 162

  Fly   723 LHSALNSGVKGETLNID------DNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCG 781
            ||:.:|.........|:      .....:::|...|:.:...::|.:.|||.|||:|:|.|:.|.
Zfish   163 LHTEINRRPSKRPAVIERKEPAYTRFRISEEAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCS 227

  Fly   782 NTSVTFDPFWDLSVPLPSSS-----RCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTI 841
            :.|.|||.|.|||:|:|...     ...|..|||||.:||.||.:..|.|.:|..|.:.||..||
Zfish   228 HYSNTFDVFCDLSLPIPKQKSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTI 292

  Fly   842 QRFPKYLVIHLKRFSETRW--SKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTA 904
            ||||:.|||||.||:.:|:  ||.:..|.||.  :.|::|.:|......|.|.|||:.||.|:..
Zfish   293 QRFPRVLVIHLNRFAMSRFSISKSTVPVSFPL--TALDLGLFGPVDCGPVLYDLYAVCNHSGTVN 355

  Fly   905 GGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYE 948
            .|||.|.|:.  ...|..:||:.| ||:||..|.|:.||:||||
Zfish   356 MGHYTAACRE--EEGWCFYNDSCV-DAISEEKLQSNQAYVLFYE 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	134/339 (40%)
Usp2	NP_001285528.1	Peptidase_C19R	626..948	CDD:239139	135/338 (40%)
usp21	XP_005162186.1	UCH	62..395	CDD:278850	134/338 (40%)
usp21	XP_005162186.1	Peptidase_C19R	63..396	CDD:239139	135/338 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1868
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469048at33208
OrthoFinder	1	1.000	-	-		FOG0000821
OrthoInspector	1	1.000	-	-		otm25084
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21646
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810