Protein Alignment Usp2 and usp32

DIOPT Version :10

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_068069823.1
• Gene: usp32 / 557981
• ZFINID: ZDB-GENE-100210-5
• Length: 1599
• Species: Danio rerio
• Alignment Length: 1298
• Identity: 231/1298 - (17%)
• Similarity: 333/1298 - (25%)
• Gaps: 701/1298 - (54%)

  Fly   258 ICY----FKPITPPLQLRHEQNQV------QQQEEQPQPS--------------------SSKSA 292
            :|:    .:|.||     .|:.|:      ::.....|||                    .:||.
Zfish   359 VCHIVLGLRPATP-----EEEGQIIRGWLERESRHGLQPSQNWFLISMQWWQQWKDYVRYDNKSI 418

  Fly   293 SHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKF 357
            ....|..:.:.:.|:.|  |||.|..                     ..|.|:...|..:..|||
Zfish   419 VMEQPSVQGSGMRSSQS--AASVEPI---------------------LNRIGLVVRSPSSPEEKF 460

  Fly   358 -NNLSGQKRQNPGSGSGIGP---GSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDN 418
             :|:|.....:..:|:.:.|   .|||         .|.....|     ..|.|..|.:||
Zfish   461 PDNISSSSEASESTGNSLTPHISSSAT---------DVCFARQH-----NISDNNNQCFSS---- 507

  Fly   419 IRVAAGY-SSSLTRAAYRTTATMNSVSTPVAVTSELGGP---------------ISGDGGETA-- 465
               |.|: .:||  |..|..|..|.   |:..|..:..|               :||...||.
Zfish   508 ---ANGHLPNSL--AVQRPGAIDNQ---PLVTTEPMKAPTLTMEGGRLKKSHQLLSGREFETVPE 564

  Fly   466 -------------TAMGQPTSKVTVRGAHSNRQP-IECDSVVLTNKASKDATTAATPTV------ 510
                         .::.:|..|.||:.     || :|...:.|.....:.||.:....:
Zfish   565 PVWRALYHWYGANLSLPRPVIKSTVKA-----QPELELFPLYLLFLRQQPATRSPQSNIWVNMGM 624

  Fly   511 --ATATATHTPATSSVSTVTVTAAAPNSASDSVSRSLARSPISSTLARSGTGS-SSTARSVLPPM 572
              ......|.|..:        ..:||            :|:...||.:|..| ..|.:.:...:
Zfish   625 SSLRMFPPHMPRGN--------VPSPN------------APLKRVLAYTGCFSRMCTIKDIHEYL 669

  Fly   573 T------PTSSRYW------------DRDSGTSRSSIGTSSALNSSSLKH------NSDDGYK-- 611
            :      ....|.|            |.|.        |..:|.....:|      |.|..:.
Zfish   670 SQRLRIKEEDMRLWLYNSENYLTLLDDEDH--------TLESLKIPDEQHLVIEVRNKDMSWPEE 726

  Fly   612 ---TASSSRDEK-----SEGLCGLRNIGNTCFMNSVIQCLSHTQELTR-FLRSHH---------- 657
               .|:||:.::     .:|..||.|:||||||||.|||:|:|:.||. |:...|
Zfish   727 MSFIANSSKIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSNTKPLTEYFISGRHLYELNRTNPI 791

  Fly   658 GSRSLSTKDQQILHEFAKLIQEMWTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDS 722
            |.|....|.      :..|:||:|:.....|.|::|:...:.....::.:.|||:||.|.|.||.
Zfish   792 GMRGHMAKC------YGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDG 850

  Fly   723 LHSALNSGVKGETLNI--DDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSV 785
            ||..||...:...:.:  .|...|::.|...||.:.|...|:|.|||.|||:|.:||.|||:.|.
Zfish   851 LHEDLNRVHEKPYVELKDSDGRPDHEVATEAWENHLRRNRSIVVDLFHGQLRSQVKCKTCGHISA 915

  Fly   786 TFDPFWDLSVPLPSSSR------------------------------------------------ 802
            .||||..||:|||..|.
Zfish   916 RFDPFNFLSLPLPMDSSMHLEITVIKLDGSTPVRYGLRLNMDEKYMGLKKQLSELCSLKPEQILL 980

  Fly   803 ----------------------------------------------------------------- 802
                                                                             
Zfish   981 AEVHTSNIKNFPLDNQKVRHSVNGFLCAFEIPVPGSPTSVTSPVQTEKPPIANGTAGNNHIGKSG 1045

  Fly   803 ----------------------------------------------------------------- 802
                                                                             
Zfish  1046 LIPNGMPSTVVPCTLEKPLANGIPNGHAVPVQDSPFIGYIIAMHRKMMRTELYFLSSQKNRPSLF 1110

  Fly   803 ----------------------------------------------------------------- 802
                                                                             
Zfish  1111 GMPLIVPCTVHTSKKDLYDAVWIQVSRLASPLPPQEASNHAQDCDDSLGYQYPFTLRVVQKDGNS 1175

  Fly   803 ---------CK------------------------------------------------------ 804
                     |:
Zfish  1176 CAWCPWYRFCRGCTVDCNEDRASLGNAYIAVDWDPTALHLRYQTSQERIVEEHPSVEQSRRAQAE 1240

  Fly   805 ---LEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS--ETRWSKLS 864
               |::||..|..||.|..||:..|:||||.|..||...:.|.|..|::|||||.  ..||.|..
Zfish  1241 PISLDSCLKAFTSEEELGEDELYYCSKCKTHRLATKKLDLWRLPPVLIVHLKRFQFVNGRWIKSQ 1305

  Fly   865 NIVEFP----------------------------------------------------------- 870
            .||:||
Zfish  1306 KIVKFPRESFDPSAFLAPREVSQSLGSLQSLQSECLVEELQRLERGDSSVSSISTTTLASPPISG 1370

  Fly   871 -----------------------------------------------------------TSDSEL 876
                                                                       .|:||.
Zfish  1371 RATPCSIRRVGSPLSRNSSPGSSPRNTGRKQGRLRLPQLGSRHRLCNSKENLEACSTNKESESEA 1435

  Fly   877 NMG------------------SYGANSN----------------SNVH----------------- 890
            ...                  |..|:||                ||.|
Zfish  1436 EQSAVTDGENLTPDANTQDTWSLDASSNDCDVIMVNGLGQDSSQSNGHSEVSADLDTPHQRNDIC 1500

  Fly   891 ----YSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYER 949
                |:|||||.|.|...|||||...|:| :.||:.:||:...:..|: .:.:.||||||||:
Zfish  1501 LESLYNLYAISCHSGIMGGGHYVTYAKNP-NEKWYCYNDSSCKEVHSD-EIDTDSAYILFYEQ 1561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UBP12	<620..>800	CDD:227847	74/197 (38%)
		Peptidase_C19R	626..948	CDD:239139	143/818 (17%)
usp32	XP_068069823.1	EFh_DMD_DYTN_DTN	<82..151	CDD:352774
		EF-hand-like motif	92..124	CDD:319999
		EF-hand-like motif	128..151	CDD:319999
		EFh	237..293	CDD:238008
		EF-hand_7	270..342	CDD:463900
		DUSP	393..>426	CDD:399383	4/32 (13%)
		UBP12	521..1560	CDD:227847	185/1082 (17%)