Protein Alignment Usp2 and usp2a

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_005157570.1
• Gene: usp2a / 494031
• ZFINID: ZDB-GENE-041212-59
• Length: 564
• Species: Danio rerio
• Alignment Length: 644
• Identity: 234/644 - (36%)
• Similarity: 333/644 - (51%)
• Gaps: 112/644 - (17%)

  Fly   334 SKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHG 398
            |:.||.|:||...|.:...|               ..||.:.|             |:.|.....
Zfish     2 SRVSSTAKRYAGSSYTSHYS---------------SYGSSLTP-------------SLGSYERDK 38

  Fly   399 SQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGE 463
            .....|||......||.|         |||.:|:...::::......|:..|..|||..|
Zfish    39 LPYKSSSSGFSSSSSSYL---------SSSASRSRNYSSSSEPDRGRPIPRTDLLGGRRS----- 89

  Fly   464 TATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVT 528
                  :..|:..|:|..|.           .|..|           ..::.::|||.||
Zfish    90 ------ESLSRTPVKGYGSG-----------LNGGS-----------GYSSYSYTPAPSS----- 121

  Fly   529 VTAAAPNSASDSVSR--SLARSPISSTLARSGTGSSSTA----RSVLPPMTPTSSRYWDRDSGTS 587
            ..:::|.|:|.|:||  |:::|.::..|:..|...:|:.    :|.|...:..|..|     .:|
Zfish   122 YLSSSPVSSSISLSRRKSVSQSDLTHDLSALGLSETSSGSGLKQSYLSRGSDVSDSY-----SSS 181

  Fly   588 RSSIG-----TSSALNSSSLKHNS--DDGYKTASSSRD----EKSEGLCGLRNIGNTCFMNSVIQ 641
            |||:|     |...|.||.||.:|  ...|::.|..|:    :.::||.||||:||||||||::|
Zfish   182 RSSLGLSRSSTQEGLGSSGLKSSSRFSSSYRSTSPVRESLNSKSAQGLVGLRNLGNTCFMNSILQ 246

  Fly   642 CLSHTQELTRFLRSHHGSRSLSTKDQ---QILHEFAKLIQEMWT-ANVHTVTPMELKRAFSTKHR 702
            |||:||.|..:...:...|.|:..::   .::.|||||||.||| ::...|:|.|.|........
Zfish   247 CLSNTQSLRDYCLHNSHRRDLNNNNRTHTALMEEFAKLIQTMWTSSSSEAVSPSEFKTQIQRYAP 311

  Fly   703 MYSDYNQQDAQEFLRFFLDSLHSALNSGV---KGETLNIDDNLSDNKKADLTWEWYTRHENSLVR 764
            .:..||||||||||||.||.||:.:|...   :|.|.:. |:|.|.:|....|..|...|:|.:.
Zfish   312 RFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRPRGNTEDF-DHLPDEEKGKKMWSKYLEREDSKIV 375

  Fly   765 DLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSS--SRCKLEACLDLFIREEVLDGDEMPTCA 827
            |||||||||:|.|:.||..|..||||||||:|:...  ....|..|:.||.:|:||||||.|||.
Zfish   376 DLFVGQLKSSLTCSECGYCSTVFDPFWDLSLPIAKKGYGEVSLMDCMRLFTKEDVLDGDEKPTCY 440

  Fly   828 KCKTRRKCTKSFTIQRFPKYLVIHLKRFSET--RWSKLSNIVEFPTSDSELNMGSYGANSNSNVH 890
            :||.||:|||.||:|:|||.||:|||||||.  |.||||..|.||..|  |::..:.::.:|:..
Zfish   441 RCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTSKLSTFVNFPMKD--LDLREFASDRSSSAV 503

  Fly   891 YSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYER 949
            |:|||:|||.|:|.||||.|.|.:|.:.:|:.:||:.|: .:|.:.:.||.||:|||||
Zfish   504 YNLYAVSNHSGTTMGGHYTAYCCNPENGEWYTYNDSRVT-PMSASQVRSSDAYVLFYER 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	159/333 (48%)
		Peptidase_C19R	626..948	CDD:239139	159/332 (48%)
usp2a	XP_005157570.1	UCH	230..559	CDD:306860	158/332 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	306	1.000	Domainoid score	I1332
eggNOG	1	0.900	-	-		E1_KOG1868
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134008
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469048at33208
OrthoFinder	1	1.000	-	-		FOG0000821
OrthoInspector	1	1.000	-	-		otm25084
orthoMCL	1	0.900	-	-		OOG6_101021
Panther	1	1.100	-	-	LDO	PTHR21646
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	1	1.000	-	-		X4948
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.850