Protein Alignment Usp2 and usp4

DIOPT Version :10

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_002662556.2
• Gene: usp4 / 449927
• ZFINID: ZDB-GENE-041008-187
• Length: 1009
• Species: Danio rerio
• Alignment Length: 799
• Identity: 162/799 - (20%)
• Similarity: 240/799 - (30%)
• Gaps: 387/799 - (48%)

  Fly   492 VVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSVSRSLARSPISSTLAR 556
            |::..|.::|.|.       ...:.|:.:::|.|....|:..|:|.|.:.        ||||:..
Zfish   228 VLVIEKKNEDGTW-------PRQSCHSKSSTSTSRNYTTSPKPSSNSSAT--------ISSTITN 277

  Fly   557 SGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKS 621
            ..:.|:|.               :..::.||.:.:|:          :||   |.::.|.|:..:
Zfish   278 GDSNSNSG---------------YMLNNSTSGNRLGS----------YNS---YSSSYSYRESAA 314

  Fly   622 E-GLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQ-----QILHEFAKLIQEM 680
            : |||||.|:||||||||.:||||:|..||.:.........::.::.     :|...:|.|:::|
Zfish   315 QPGLCGLSNLGNTCFMNSALQCLSNTPPLTEYFLEDRYEAEINRENPLGMRGEIAEAYADLVKQM 379

  Fly   681 WTANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDD--NLS 743
            |.:....|.|...|.........:|.|.|||:||.|.|.||.||..||...|...|.:.|  ...
Zfish   380 WLSRSSYVAPRTFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLALRDAEGRP 444

  Fly   744 DNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSSSRCKLEAC 808
            |...|...|..:....:|::.|:|.|..||||.|..|...|||||||..|::|||......:|..
Zfish   445 DEIVAKEAWANHRLRNDSIIVDIFHGLFKSTLVCPECSKVSVTFDPFCYLTLPLPMKKDRTMEVY 509

  Fly   809 L---------------------------------------------------------------- 809
            |
Zfish   510 LVRTDPQFRAMQFRVVVPKMGAVADLCSALAKLSGVPSENMVVADVYNHRFHKIYKRDDGLNQIM 574

  Fly   810 ---DLFIRE-------------------------------------------------------- 815
               |:|:.|
Zfish   575 EKDDIFVYEVLEEDSERMNLPVYFRERHAKHSGGSSGTMLFGQPLLITVPRLNLTVDTLYERVLE 639

  Fly   816 ----------------------------------------------------------------- 815
                                                                             
Zfish   640 RIGRYVKRSQGTITESRASASATSSSSSQSPECLASVSSHGTGLSGCSSPVSDGASCSAGSNGSN 704

  Fly   816 ---------EVLDGDE------------------------------------------------- 822
                     .|.||||
Zfish   705 HSGTCNGPNGVCDGDEEAMDHQESPEPENSHSDTVDGEEDSEPENGPNSSGGKSFNSRPKLFSFS 769

  Fly   823 ----------------------------------------------------------------- 822
                                                                             
Zfish   770 MVNSYGTANISSLPFDGNLLKLTTHSTVAIDWDSDTKRLCYDDQEAEAYDKHESMLHAQKKKTTV 834

  Fly   823 -----------MPT--------CAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSETR-W-SKLSNI 866
                       |.|        |..||..::.||.|.:...|:.||:||||||..| | .||..:
Zfish   835 ALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPRILVVHLKRFSYNRCWRDKLDTV 899

  Fly   867 VEFPTSDSELNMGSYGANSNSNVH-YSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSD 930
            |:||..|  |||..:..:..::.: |.|.|:|||.|...||||.|..|:....||:.|:|:.||
Zfish   900 VDFPIRD--LNMSEFVCDPKADPYIYDLIAVSNHYGGMGGGHYTAYGKNKADGKWYYFDDSSVS- 961

  Fly   931 ALSENHLVSSSAYILFYER 949
            |.:|:.:|:.:||:|||:|
Zfish   962 AATEDQIVTKAAYVLFYQR 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UBP12	<620..>800	CDD:227847	71/187 (38%)
		Peptidase_C19R	626..948	CDD:239139	132/661 (20%)
usp4	XP_002662556.2	UBP12	8..981	CDD:227847	162/799 (20%)