Protein Alignment Usp2 and USP50

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_987090.2
• Gene: USP50 / 373509
• HGNCID: 20079
• Length: 334
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 91/308 - (29%)
• Similarity: 144/308 - (46%)
• Gaps: 26/308 - (8%)

  Fly   622 EGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQQILHEFAKLIQEMWTANVH 686
            :|:.||.|:||||.:|::.|||.....|..:..:.....:|.....::...||.|:.:||..:..
Human    41 QGVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQNDCSEVATAFAYLMTDMWLGDSD 105

  Fly   687 TVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSAL--------NSGVKGETLNIDDNLS 743
            .|:|.....|....:..::...||||||||...|:.||.||        .|..||.|..
Human   106 CVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQR------ 164

  Fly   744 DNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSSSRCKLEAC 808
                  ...:|.|. |.|::..||..||..::.|..|...:...:.|...|:|:||...|.|..|
Human   165 ------CCRKWITT-ETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDC 222

  Fly   809 LDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRF--SETRWSKLSNIVEFPT 871
            |..|.:::.|..:....|:.|:|:::.....:|.:.||.::.|||||  ..|...||...:.:|.
Human   223 LQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPL 287

  Fly   872 SDSELNMGSYGAN-SNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSR 918
            ::  |::..|..: ......|:|.|:.||.|...||||.|.||:.|::
Human   288 TN--LDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQ 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	90/306 (29%)
		Peptidase_C19R	626..948	CDD:239139	90/304 (30%)
USP50	NP_987090.2	Peptidase_C19R	45..333	CDD:239139	90/302 (30%)
		UCH_1	45..326	CDD:290159	86/295 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1868
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469048at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820