Protein Alignment Usp2 and Usp21

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_038947.2
• Gene: Usp21 / 30941
• MGIID: 1353665
• Length: 566
• Species: Mus musculus
• Alignment Length: 549
• Identity: 185/549 - (33%)
• Similarity: 264/549 - (48%)
• Gaps: 68/549 - (12%)

  Fly   446 PVAVTSELGGPISGDGG---ETATAMGQPTSKVTV----RGAHSN---RQPIECDSVVLTNKASK 500
            |.|.:.|...|:.|...   ......|.|..::..    ||..|.   |.|:..|..|....:..
Mouse    31 PRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKLELGRGRTSGSRPRGPLRADHGVPLPGSPP 95

  Fly   501 DATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASD---SVSRSLARSPISSTLARSGTGSS 562
            .|.....|:......:.:.::..:..:.:.......|.:   ::|| ||..|...||.||   :|
Mouse    96 PAVALPLPSRTNLARSKSVSSGDLRPMGIALGGHRGAGELGAALSR-LALRPEPPTLRRS---TS 156

  Fly   563 STARSVLP-PMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCG 626
            .......| |.|..|.|   .:..||..|....||..|...  .|||  |.|..:. ....|..|
Mouse   157 LRRLGGFPGPPTLLSIR---TEPPTSHGSFHMISARPSEPF--YSDD--KMAHHTL-LLGSGHVG 213

  Fly   627 LRNIGNTCFMNSVIQCLSHTQELTRF-LRSHH------GSRSLSTKDQQILHEFAKLIQEMW-TA 683
            |||:|||||:|:|:||||.|:.|..| ||...      |.|:     |::...||.:|..:| ..
Mouse   214 LRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRA-----QELTEAFADVIGALWHPD 273

  Fly   684 NVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALN-----------SGV------ 731
            :...|.|...:..|......:|.|:||||||||:..::.||..:|           ||.
Mouse   274 SCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPC 338

  Fly   732 -KGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSV 795
             .|..|:.:..|||:.:|:|.|:.|...|:|.:.|||||||||.|||..||..|.||:.|.|||:
Mouse   339 RGGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSL 403

  Fly   796 PLP----SSSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS 856
            |:|    :..:..|..|..||.:||.|:.:..|.|.:|:.:.:.||..|:||||:.||:||.|||
Mouse   404 PIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFS 468

  Fly   857 ETRWS-KLSNI-VEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRK 919
            .:|.| |.|:: |:||.  ..|::|.:.::...:..|.|||:.||.||...|||.|||:  ....
Mouse   469 TSRGSIKKSSVGVDFPL--QRLSLGDFASDKAGSPVYQLYALCNHSGSVHYGHYTALCR--CQTG 529

  Fly   920 WHEFNDNIVSDALSENHLVSSSAYILFYE 948
            ||.:||:.|| .:|||.:.||..|:|||:
Mouse   530 WHVYNDSRVS-PVSENQVASSEGYVLFYQ 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	139/354 (39%)
		Peptidase_C19R	626..948	CDD:239139	140/353 (40%)
Usp21	NP_038947.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		15/71 (21%)
		Nuclear export signal. /evidence=ECO:0000250	134..152		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..169		8/25 (32%)
		UCH	212..556	CDD:278850	139/353 (39%)
		Peptidase_C19R	213..557	CDD:239139	140/353 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..349		4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847274
Domainoid	1	1.000	303	1.000	Domainoid score	I1391
eggNOG	1	0.900	-	-		E1_KOG1868
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000821
OrthoInspector	1	1.000	-	-		otm43678
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21646
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.800